README.md

In cTRAP: Identification of candidate causal perturbations from differential gene expression data

cTRAP

cTRAP is an R package designed to compare differential gene expression results with those from known cellular perturbations (such as gene knock-down, overexpression or small molecules) derived from the Connectivity Map (Subramanian et al., Cell 2017). Such analyses allow not only to infer the molecular causes of the observed difference in gene expression but also to identify small molecules that could drive or revert specific transcriptomic alterations.

Installing

cTRAP is available in Bioconductor and can be installed with:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("cTRAP")

If you prefer, you can install cTRAP from GitHub instead:

install.packages("remotes")
remotes::install_github("nuno-agostinho/cTRAP")

cTRAP documentation built on Nov. 8, 2020, 10:58 p.m.