Nothing
# require(dfoptim)
gammafit <- function(time, event) {
gammaLik <- function(x) {
ie <- which(event==0)
it <- which(event==1)
if(length(it)>0) dg <- dgamma(time[it], shape=x[1], scale=x[2], log=TRUE)
else print("count of noncensored times is 0")
if(length(ie) > 0) sg <- pgamma(time[ie], shape=x[1], scale=x[2],
lower.tail=FALSE, log.p=TRUE) else sg = 0
return(-(sum(dg)+sum(sg)))
}
no = length(time)
s = log(sum(time)/no) - sum(log(time))/no
sx = (3 - s + sqrt((s-3)*(s-3) + 24*s))/(12*s)
xx = c(sx, max(time)/2)
return(nmkb(xx, gammaLik, lower=c(0.01, 0.1), upper=c(sx*10, max(time))))
}
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