SubgrpID-package: Patient subgroup identification for clinical drug development

In SubgrpID: Patient Subgroup Identification for Clinical Drug Development

Description

Prognostic and predictive biomarker signature development for Exploratory Subgroup Identification in Randomized Clinical Trials

Details

Package:	SubgrpID
Type:	Package
Version:	0.10
Date:	2017-01-25
License:	GPL-3

Author(s)

Xin Huang, Yan Sun, Saptarshi Chatterjee and Paul Trow Maintainer: Xin Huang <[e-mail]>

References

Huang X. et al. (2017) Patient subgroup identification for clinical drug development. Statistics in Medicine, doi: 10.1002/sim.7236.

Chen G. et al. (2015) A PRIM approach to predictive-signature development for patient stratification Statistics in Medicine, 34, 317-342.

Examples

  ## Not run: 
    data(Sepsis.train)
    data(Sepsis.test)
    
    yvar="survival"
    xvars=names(Sepsis.train)[2:12]
    trtvar="THERAPY"
    
    set.seed(123)
    subgrp <- SubgrpID(data.train=Sepsis.train,
                      yvar=yvar,
                      trtvar=trtvar,
                      trtref="active",
                      xvars=xvars,
                      type="b",
                      des.res = "smaller",
                      method="AIM.Rule")
    subgrp$res
    subgrp$train.stat
    subgrp$train.plot
  
## End(Not run)

SubgrpID documentation built on May 2, 2019, 8:02 a.m.