R/plot.TrialLevelMA.R

In Surrogate: Evaluation of Surrogate Endpoints in Clinical Trials

plot.TrialLevelMA <-  
  function(x, Weighted=TRUE, Xlab.Trial, Ylab.Trial, Main.Trial, 
  Par=par(oma=c(0, 0, 0, 0), mar=c(5.1, 4.1, 4.1, 2.1)),...) {
 
  Object <- x 
    if (missing(Xlab.Trial)) {Xlab.Trial <- expression(paste("Treatment effect on the surrogate endpoint ", (alpha[i])))}
    if (missing(Ylab.Trial)) {Ylab.Trial <- expression(paste("Treatment effect on the true endpoint  ",(beta[i])))}
    if (missing(Main.Trial)) {Main.Trial <- c("Trial-level surrogacy")}
    dev.new()
    par=Par
    if (Weighted==TRUE){
      plot(Object$Alpha.Vector, Object$Beta.Vector, cex=(Object$N.Vector/max(Object$N.Vector))*8, xlab=Xlab.Trial, ylab=Ylab.Trial, main=Main.Trial,...)
      abline(lm(Object$Beta.Vector ~ Object$Alpha.Vector))}
    
    if (Weighted==FALSE){
      plot(Object$Alpha.Vector, Object$Beta.Vector, xlab=Xlab.Trial, ylab=Ylab.Trial, main=Main.Trial, ...)
      abline(lm(Object$Beta.Vector ~ Object$Alpha.Vector))}
  
}