inst/shiny-examples/reference.md

In caffsim: Simulation of Plasma Caffeine Concentrations by Using Population Pharmacokinetic Model

Reference range

• Below 10 mg/L: generally considered safe (Green horizontal line)
• Over 40 mg/L: several fatalities (Blue horizontal line)
• Over 80 mg/L: fatal caffeine poisoning (Red horizontal line)
• Reference: de Wijkerslooth LR et al.(2008), Seifert et al.(2013), Banerjee et al. (2014), Cannon et al. (2001)

caffsim documentation built on May 2, 2019, 3:45 p.m.