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# Step-down Tippett procedure for strong FWE control
#
# @param T (iter+1) X k matrix of permutation test statistics
#
# @return The global p-value and a vector of adjusted p-values
#
# @author Alessandra Cabassi \email{alessandra.cabassi@mail.polimi.it}
FWE.maxT = function(T){
ord = order(T[1,],decreasing=TRUE) # put the vector of observed test staiistics in decreasing order and store the order
T.ord = T[,ord] # put the columns of matrix T in the new order 'ord'
k = dim(T)[2] # number of tests
p.ris = array(5,dim=c(k,1)) # create vector of adjusted p-values
# Compute smallest p-value
Tcomb = apply(T.ord,1,max) # combine vectors of p-values with max comb. fct.
p.ris[1] = p.glob=mean(Tcomb[-1] >= Tcomb[1]) # the first adjusted p-value corresponds with the global p-value
# Compute the other p-values
if(k>2){ # apply general step-down algorithm for p-value adjustement
for(j in 2:(k-1)){
Tcomb = apply(T.ord[,j:k],1,max)
p.ris[j] = max(mean(Tcomb[-1] >= Tcomb[1]),p.ris[(j-1)])
}
}
# Compute greatest p-value
Tcomb = T.ord[,k]
p.ris[k] = max(mean(Tcomb[-1] >= Tcomb[1]),p.ris[k-1]) # last adjusted p-value
# Put the ajusted p-values in the correct order
p.ris[ord] = p.ris
rownames(p.ris) = colnames(T)
return(p.ris)
}
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