pca_scaled: PCA for autoscaled data
In mseapca: Metabolite set enrichment analysis for factor loading in principal component analysis
Description
Usage
Arguments
Details
Value
Author(s)
References
Examples
Description
This function performs principal component analysis (PCA).
In this function, data matrix is automatically scaled to zero mean and unit variance (autoscaling) for each metabolites.
PC scores, factor loadings and the results of statistical test (p-value and q-value by Benjamini and Hochberg) are returned.
In this function, factor loading is defined as a correlation coefficient between PC score and each metabolite levels.
Usage
1
Arguments
D
dataframe of metabolite IDs and data matrix (metabolites * samples)
Details
Blank must be set to missing values in data matrix.
If standard deviation of metabolite levels is equal to zero,
it is removed from PCA computation and the results of factor loadings are set to NA.
Value
list of PC scores, factor loadings, p-value and q-value (by Benjamini and Hochberg),
and contribution ratios
Author(s)
Hiroyuki Yamamoto
References
Benjamini, Yoav and Hochberg, Yosef (1995). "Controlling the false discovery rate: a practical and powerful approach to multiple testing". Journal of the Royal Statistical Society, Series B (Methodological) 57 (1): 289-300.
Examples
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
# --------------
# Sample data
# --------------
X <- matrix(runif(1000),nrow=100,ncol=10) # 100(metabolites)*10(samples)
M <- as.character(c(1:100)) # metabolite IDs
D <- data.frame(M,X) # dataframe of metabolite IDs and data matrix
# ---------------------------
# PCA for autoscaled data
# ---------------------------
A <- pca_scaled(D) # automatically scaled in pca_scaled function
# ---------
# Result
# ---------
A[["score"]] # PC score
A[["factor.loading"]] # factor loading
A[["p.value"]] # p-value of factor loading
A[["q.value"]] # q-value of factor loading
Example output
Loading required package: XML
PC score (PC1) PC score (PC2) PC score (PC3) PC score (PC4) PC score (PC5)
X1 -2.3516103 4.430179 -5.7566353 3.74186362 -1.314678982
X2 -5.6110382 3.859811 -2.3897620 -5.28827632 -0.005327863
X3 5.0881741 -4.010448 -5.8244445 -3.02079885 -0.844927386
X4 4.8067274 2.432981 0.7358249 5.65192956 -1.386052279
X5 0.6272150 -5.369643 -0.7186427 -0.02975301 -1.762402995
X6 -3.6364909 1.550733 2.9955384 1.51613161 -0.168443597
X7 -0.1371614 -2.588705 2.6107246 1.17927976 -0.347931958
X8 -3.0555710 -2.157531 4.5398183 -1.43315727 -4.631854390
X9 6.9192142 4.990746 3.6383635 -3.91850869 2.283473774
X10 -2.6494587 -3.138124 0.1692150 1.60128958 8.178145677
PC score (PC6) PC score (PC7) PC score (PC8) PC score (PC9) PC score (PC10)
X1 0.05450493 -2.0843406 3.1943400 2.1017053 -3.122502e-17
X2 1.14887292 0.9369788 -4.0767302 -0.1013663 -2.706169e-16
X3 -2.92285531 -0.5498972 0.4680440 -2.7752404 1.651457e-15
X4 2.18148108 0.4189789 -3.9021974 -2.2474831 8.153200e-16
X5 4.07721777 4.3269265 0.7483305 3.0414634 1.387779e-15
X6 -4.00285660 4.8029513 2.3293806 -2.3344426 -2.498002e-16
X7 -5.16450674 -1.9674867 -2.8921264 3.8193254 1.467576e-15
X8 2.23397657 -4.0789749 1.6740237 -1.9455820 6.591949e-16
X9 0.65924058 -0.1697410 2.1154270 1.5310159 -3.955170e-16
X10 1.73492480 -1.6353950 0.3415081 -1.0893958 2.040035e-15
Metabolite ID factor loading(PC1) factor loading(PC2) factor loading(PC3)
1 1 -0.044776091 -0.125057417 0.61401858
2 2 0.450222827 0.024642016 0.52953739
3 3 0.643099256 0.048805999 0.01896986
4 4 0.178544889 0.032123778 0.11768729
5 5 0.676159525 0.033123527 0.05986064
6 6 -0.141378368 0.403401425 -0.60683064
7 7 -0.306331914 -0.521385445 -0.03061141
8 8 -0.088560304 0.651814990 0.09364102
9 9 -0.826820298 -0.018956466 0.30956419
10 10 -0.750976206 0.132167201 -0.30522540
11 11 0.529580080 -0.076605005 0.05174051
12 12 -0.726601417 -0.054842440 0.43586011
13 13 -0.102008629 0.133168135 -0.60760875
14 14 0.805441983 0.298526291 -0.12978491
15 15 -0.323584219 0.405780146 0.74001613
16 16 0.214403581 -0.232395361 -0.48467757
17 17 -0.161902499 -0.155749585 -0.58054188
18 18 -0.504446530 -0.096246677 -0.07162361
19 19 0.448595273 -0.441393008 -0.48339073
20 20 0.054185503 0.425114842 -0.16721519
21 21 -0.732529421 0.175161191 -0.26197625
22 22 0.453336165 0.021415559 0.22812789
23 23 -0.565141758 0.047359842 -0.38453858
24 24 0.207277448 0.580240634 -0.18133640
25 25 0.053518040 -0.213470212 0.02733561
26 26 0.465153773 -0.154682311 -0.06240538
27 27 -0.590715338 -0.080136280 0.14311246
28 28 0.266752945 0.373340454 0.01725729
29 29 -0.030330549 -0.702718481 0.21607301
30 30 0.051305532 0.534602358 0.71083371
31 31 -0.595025412 -0.163208816 0.35537571
32 32 -0.089353544 0.240330582 -0.20273080
33 33 -0.023208928 0.185698537 0.30258308
34 34 0.414594194 0.448047170 -0.37317974
35 35 0.191689298 0.315422479 0.11733678
36 36 -0.007938960 0.457630720 0.23684426
37 37 -0.526106151 0.103772330 -0.49140977
38 38 0.344452257 0.162040318 -0.56240387
39 39 -0.697140881 0.456390204 -0.18017724
40 40 0.212979023 0.888134159 -0.07074584
41 41 0.022566516 -0.031578239 0.73313024
42 42 0.117442740 0.015578264 0.70887042
43 43 0.718622263 -0.520405080 0.31186311
44 44 -0.367186431 -0.255481580 0.69096021
45 45 -0.146491037 0.290991948 -0.72081624
46 46 0.631038990 -0.282309903 -0.09872481
47 47 -0.234977119 -0.800584674 0.40373306
48 48 -0.176606278 0.102168228 -0.26273689
49 49 -0.127516671 -0.103915162 -0.29666615
50 50 -0.523969704 -0.298564629 0.64989080
51 51 -0.802565720 0.213245378 0.05388928
52 52 0.388193246 0.550607420 0.18223272
53 53 0.338022848 -0.578757791 -0.52017309
54 54 0.507915022 0.221792266 0.09383125
55 55 -0.359679373 0.086863810 -0.46524072
56 56 -0.538193511 0.059689110 -0.42942259
57 57 -0.112003432 -0.353366466 -0.10023765
58 58 0.449132555 -0.427684570 0.26303420
59 59 0.230079570 0.609189711 -0.44726406
60 60 -0.670601929 -0.475243075 0.32004561
61 61 -0.160997242 0.125097383 0.22112579
62 62 0.160681121 -0.081029892 0.15109652
63 63 0.578968765 0.538399062 0.40248005
64 64 -0.234087504 0.266313341 -0.08913382
65 65 0.748312098 -0.077318410 -0.05814875
66 66 0.170720900 0.419950084 -0.08787539
67 67 -0.466746964 -0.072489121 -0.53914516
68 68 0.016327482 0.544574678 -0.19053815
69 69 -0.481439264 0.002282796 0.23247437
70 70 -0.300898671 -0.432184518 -0.39552362
71 71 0.700518659 -0.258397398 0.16759799
72 72 0.368243212 -0.491140871 -0.05584632
73 73 0.021423066 -0.927513800 -0.11715827
74 74 0.050108926 0.651690146 0.11625659
75 75 -0.454078357 -0.165075231 -0.13039297
76 76 -0.637470379 -0.548437721 0.34264425
77 77 -0.390233239 -0.467081075 -0.18289614
78 78 -0.271524113 -0.708384700 -0.42705597
79 79 0.072747439 0.460386120 -0.04895646
80 80 -0.215021491 -0.185753837 0.32646899
81 81 0.417310824 -0.669156455 -0.22466718
82 82 -0.008950141 -0.687240148 0.37506232
83 83 -0.262465334 0.031651775 -0.88797764
84 84 0.246551663 -0.315595735 -0.64309343
85 85 -0.610944880 0.089020421 -0.16196925
86 86 0.542528849 -0.625797880 -0.10320343
87 87 -0.466136419 0.246226864 -0.22287369
88 88 0.018352668 -0.696680419 -0.29421870
89 89 -0.200673125 0.437129255 0.35123547
90 90 -0.107416679 -0.578638683 -0.52288503
91 91 -0.660521163 -0.202297684 -0.20859413
92 92 0.203245132 0.069914652 0.46756689
93 93 0.106046884 0.455182615 0.22381942
94 94 0.412974829 -0.057625790 -0.60202867
95 95 -0.819064094 -0.075039925 0.46499655
96 96 -0.448147349 0.720140532 -0.46853472
97 97 -0.196359903 0.166496275 0.29391021
98 98 0.292239785 0.013696529 0.20582504
99 99 -0.697897176 0.218965296 0.02370942
100 100 0.379727786 -0.120629278 -0.27825893
factor loading(PC4) factor loading(PC5) factor loading(PC6)
1 0.088461928 -0.243859201 -0.667571786
2 -0.080746887 -0.211894277 0.507518614
3 -0.001443753 0.254911014 -0.413687241
4 -0.662745012 -0.118381690 -0.608840967
5 0.044703458 -0.176878843 -0.267683569
6 -0.562931120 -0.247797497 -0.253253175
7 0.123737982 -0.219672585 -0.417380768
8 0.188456183 -0.553962577 -0.173643250
9 -0.010636544 -0.078638950 -0.237487413
10 0.022734471 0.158307499 -0.263648499
11 0.353878386 -0.693937749 -0.075816556
12 -0.170366394 0.181487175 -0.155233411
13 -0.538112600 -0.114257857 -0.244561599
14 -0.385609857 0.172477408 -0.168717834
15 -0.163643610 0.065275519 0.015924400
16 0.569796873 -0.270806732 -0.157789835
17 -0.053220935 -0.608501736 -0.072953729
18 0.378647063 -0.263357124 0.596729925
19 0.195968090 0.457812701 0.107388493
20 0.677594877 0.331617519 0.133352964
21 -0.144509519 0.145687293 0.333404585
22 0.542251690 -0.160241964 -0.381971221
23 0.338352576 0.105471885 0.516622615
24 -0.241320764 0.099259923 -0.429162573
25 0.734295602 -0.094267280 0.446833355
26 -0.502464715 -0.299584396 0.188040734
27 -0.096712983 -0.498961648 0.374776851
28 0.334542576 -0.538466354 -0.233815465
29 -0.098883191 -0.547102483 -0.306723508
30 -0.331839519 -0.245789862 0.020066741
31 -0.157639837 0.420417757 0.150582645
32 0.444000716 -0.357691484 -0.090656180
33 -0.442852482 0.167117007 0.753360467
34 0.282644501 -0.292881634 0.060392157
35 0.663032321 -0.486452749 -0.168992546
36 -0.551582725 0.597707398 -0.163887557
37 0.372906046 0.186371163 0.409803408
38 -0.250131921 0.326074899 0.018721917
39 0.165737282 0.165704262 -0.326040152
40 -0.115500152 0.099768090 0.328104298
41 0.268575699 0.161406278 0.059742620
42 0.384445914 0.159236418 -0.486298024
43 -0.215598733 -0.075506481 -0.121308256
44 -0.041129660 0.207155776 0.093469119
45 0.055186013 -0.541034591 0.201724165
46 -0.096212863 -0.115277409 0.656574704
47 0.285274419 -0.027144453 0.089490636
48 0.234109447 0.696475569 0.269521144
49 0.020548500 0.272769647 0.271318262
50 0.241890333 0.121062680 0.105735735
51 -0.257703472 -0.415027205 0.178963470
52 0.053973462 0.167803722 -0.001099438
53 -0.147738816 -0.074573061 0.145731270
54 0.359223649 0.469103125 -0.260039009
55 0.421894954 0.337613800 -0.274775646
56 -0.120257694 -0.645595024 -0.149238641
57 -0.538519592 -0.188697787 -0.380845697
58 0.130251928 -0.436399715 0.177488656
59 0.088853324 -0.204956542 0.556651287
60 -0.093087421 0.068563101 0.384590379
61 0.829382463 -0.092127961 0.283754119
62 -0.603048151 -0.361872946 -0.189797225
63 -0.009368147 0.006798874 0.089707261
64 0.646992354 0.262961434 -0.283300960
65 0.282736205 -0.205873706 0.269987830
66 -0.201569207 -0.570475406 0.364164179
67 0.321577520 0.216418902 -0.429608857
68 -0.139904895 -0.448984330 -0.405175580
69 0.743993364 -0.223936513 -0.229427835
70 -0.437907182 -0.272939295 0.271993889
71 0.215080866 -0.307254470 0.039432396
72 0.039237223 -0.650794949 0.327976338
73 0.172244815 0.252809176 -0.078555219
74 -0.064725919 0.393014557 0.339532464
75 0.136853716 -0.327376006 0.557371290
76 0.191857997 -0.245429028 -0.055377648
77 -0.562570431 0.167211764 -0.100790236
78 -0.291406261 -0.377060498 -0.023096348
79 0.455936101 -0.394822043 -0.019748607
80 -0.429619050 -0.444782881 0.042138294
81 0.182778135 0.447863310 -0.040235308
82 -0.007581458 -0.093238875 0.543362109
83 -0.193514624 -0.261976508 -0.052181938
84 0.030255888 0.630478149 -0.095288986
85 0.015469017 -0.673989162 -0.158145293
86 -0.133503392 0.213314615 0.372660813
87 -0.054228767 0.518684264 0.448648038
88 -0.184209038 0.170364152 -0.419494119
89 -0.565687973 -0.261097160 0.334900546
90 0.447102971 -0.022314020 -0.022715103
91 0.277197715 0.302959034 -0.457561522
92 0.186998309 0.328792880 0.363698978
93 -0.134844070 0.128473468 0.095564387
94 0.575100937 0.061494237 0.066281490
95 -0.016553014 -0.084779638 -0.073316820
96 0.008557851 -0.068952095 0.139106664
97 0.349607829 -0.228083103 -0.066347154
98 0.592458317 -0.618339601 0.015521081
99 0.052334557 -0.254720390 0.029250652
100 -0.503607393 -0.260335861 0.301837568
factor loading(PC7) factor loading(PC8) factor loading(PC9)
1 0.003463811 -0.1745123276 0.248848278
2 0.278622102 0.3261365115 -0.152619277
3 0.386367740 0.4119477847 -0.169060983
4 0.277830431 0.1734948170 -0.148380556
5 0.658025802 -0.0052881120 0.012763079
6 -0.002317765 0.0707044204 0.039991475
7 -0.202213336 0.4715966844 -0.363749107
8 -0.182087404 0.0200155665 -0.390418952
9 0.004299749 0.1906989099 0.347989664
10 0.070126668 0.2921513875 0.374226121
11 -0.224343602 0.1329746009 0.174526711
12 -0.144977568 -0.4037334101 -0.094814417
13 -0.201477556 -0.1196414121 0.430504837
14 0.175489282 -0.0803580756 -0.033735887
15 0.258954698 0.2508513780 -0.147425226
16 0.410046271 0.2422707745 0.123998752
17 0.428427110 0.1441223728 0.172483779
18 -0.336711100 -0.1806583546 0.127715908
19 -0.031715309 -0.2314918633 -0.236950007
20 0.420270537 0.1349309659 -0.081600765
21 -0.395702611 -0.1788545871 -0.149170107
22 0.446939231 -0.0522883751 0.271809147
23 0.232762691 -0.2358064159 0.167967468
24 -0.322881012 0.3199836141 0.358557608
25 -0.366984647 0.2211174642 -0.139685329
26 0.356011488 0.4642584055 0.189604732
27 0.356276412 0.2226170917 0.221104783
28 -0.524890499 0.1957381063 -0.137128024
29 -0.048908938 0.1914089480 0.127950997
30 0.035236768 0.0703225348 -0.170774166
31 0.378074100 0.1318806876 -0.329251674
32 0.660208063 -0.2183211794 -0.276261073
33 0.105123124 -0.2637786436 -0.034531499
34 0.409064015 0.3870089117 0.040966127
35 0.195480982 0.2619224339 0.195890689
36 0.181458898 0.1130551621 0.018717009
37 0.325971848 0.1020875046 0.112020507
38 0.348092825 -0.1495363577 0.475422339
39 0.027941713 0.1517902450 0.296965973
40 -0.155678703 -0.0509967535 -0.055405438
41 -0.367065684 0.3856888065 0.275257114
42 0.103935525 -0.2352814085 -0.087559374
43 -0.016420703 -0.1624474221 0.148133233
44 0.033949621 0.4741502807 0.207760852
45 0.068538335 -0.1081070371 -0.146447306
46 -0.127424770 0.1938581517 -0.069929476
47 0.093488042 -0.1000359873 -0.178816788
48 -0.060524833 0.4697281284 0.229142603
49 -0.326076796 0.7858485703 -0.112281604
50 0.189667455 -0.2845424829 0.112567936
51 0.122335677 0.1309716709 -0.068588911
52 -0.043252143 -0.6750629805 -0.155805965
53 0.389926273 0.1059548003 -0.261353234
54 -0.080121641 0.1570865484 -0.486015327
55 -0.145620570 0.0633110161 -0.503927352
56 -0.075796490 -0.2280163564 -0.105440075
57 0.379474399 0.1577218344 -0.461529129
58 0.445235880 0.0269653285 0.329096107
59 0.072262944 -0.0609753538 0.084873271
60 0.206372621 0.1343431169 0.009706611
61 -0.130695851 0.2169121790 -0.261767815
62 -0.642698904 0.0258483181 0.020333963
63 0.214095245 -0.3986363706 0.001521939
64 -0.045884504 0.3201840482 -0.440119231
65 0.415999050 -0.0343664546 -0.247418985
66 -0.090295643 0.4320047084 -0.305458612
67 -0.024190977 0.0115699997 -0.388179099
68 -0.038887837 -0.0256201116 -0.528555423
69 0.121638790 -0.1315848638 0.160453421
70 0.102286588 0.4266679215 -0.183003558
71 0.234079449 0.1376830217 0.445472226
72 -0.031322456 -0.1630656942 -0.244632682
73 -0.157786035 -0.0008257378 0.029738010
74 0.504672077 -0.1451081507 -0.097933615
75 0.127030636 -0.2267288053 -0.495430328
76 0.228031081 -0.1157996391 0.099615201
77 0.439103193 0.1110667789 -0.190659147
78 0.010477088 -0.0454087469 0.110867390
79 -0.462105116 -0.2727910809 0.358116465
80 -0.465852487 -0.3579260474 -0.288738112
81 -0.034030184 -0.2955351950 0.059148929
82 -0.259037408 0.1257302364 0.006878409
83 -0.002229071 0.1745422796 -0.048304181
84 0.064421217 -0.0680574054 -0.098805076
85 0.100833054 0.2449781486 -0.207112209
86 -0.176558660 -0.0921330288 -0.248041725
87 0.188006082 0.1484413193 0.376531790
88 0.432603960 0.0031533057 -0.040577936
89 0.363103536 -0.0998764242 -0.055941875
90 -0.161722850 -0.2587325588 0.293629704
91 0.074654916 0.1639131800 0.262392353
92 0.329130776 0.5706218880 -0.160928811
93 -0.313164878 0.6504657475 0.408005976
94 -0.154132130 -0.2897305582 0.130675801
95 0.230180392 -0.1891646518 -0.075352517
96 0.101481017 -0.1589600667 0.035941450
97 0.464610500 -0.6723429245 0.027949284
98 -0.115121419 0.3258585881 0.137898447
99 0.516029200 -0.1589508212 0.323114705
100 -0.084303733 -0.2574525064 0.527197643
factor loading(PC10)
1 -0.011562029
2 -0.211987331
3 -0.046133743
4 -0.296054785
5 -0.113518490
6 -0.495295492
7 0.323547593
8 -0.666414943
9 -0.222562444
10 -0.219715356
11 0.049946470
12 -0.006343244
13 -0.137025817
14 -0.179436025
15 -0.625553703
16 0.216680304
17 -0.104569910
18 0.144363309
19 0.741265088
20 -0.212046816
21 -0.094961763
22 0.001351582
23 0.033454735
24 -0.478279231
25 0.368466219
26 -0.138868574
27 -0.309199812
28 -0.288510102
29 0.373100032
30 -0.713575369
31 -0.020500058
32 -0.289196960
33 -0.214945155
34 -0.450957140
35 -0.343752307
36 -0.455048820
37 -0.052398480
38 -0.023695069
39 -0.441670461
40 -0.677866489
41 0.031552060
42 0.047682692
43 0.483199513
44 0.016319587
45 -0.296309412
46 0.306051685
47 0.660826803
48 0.083562346
49 0.111303179
50 0.190132320
51 -0.531139792
52 -0.245315144
53 0.477147993
54 0.061827803
55 0.134011975
56 -0.215955537
57 0.021265198
58 0.216902142
59 -0.460374912
60 0.200840499
61 -0.015311081
62 -0.028571872
63 -0.400709194
64 -0.097672872
65 0.122973893
66 -0.579426660
67 0.192524766
68 -0.585504854
69 -0.011723966
70 0.117385409
71 0.194313193
72 0.371212079
73 0.962404979
74 -0.553710559
75 0.065686434
76 0.279304906
77 0.178976217
78 0.473604148
79 -0.241260677
80 0.040199096
81 0.900465498
82 0.556747215
83 -0.090660461
84 0.576458579
85 -0.396646910
86 0.733617094
87 -0.189709316
88 0.555326441
89 -0.703257529
90 0.732399176
91 0.186837185
92 -0.137834584
93 -0.467516537
94 0.428741574
95 -0.164329467
96 -0.633603777
97 -0.168918716
98 -0.072606251
99 -0.437240500
100 0.091630393
Metabolite ID p-value(PC1) p-value(PC2) p-value(PC3) p-value(PC4)
1 1 0.902248440 0.7306752546 0.058962988 0.807996755
2 2 0.191662197 0.9461283108 0.115452935 0.824513350
3 3 0.044874077 0.8934908265 0.958518356 0.996841798
4 4 0.621647322 0.9298017049 0.746095159 0.036757016
5 5 0.031824970 0.9276217315 0.869523067 0.902406373
6 6 0.696842583 0.2476833603 0.062845926 0.090214935
7 7 0.389319350 0.1222173885 0.933100254 0.733429587
8 8 0.807786575 0.0411385058 0.796947012 0.602084026
9 9 0.003174949 0.9585476278 0.384075586 0.976735192
10 10 0.012299948 0.7158818584 0.391122397 0.950294041
11 11 0.115418140 0.8334064698 0.887120137 0.315765821
12 12 0.017301963 0.8803923378 0.207973512 0.637953267
13 13 0.779163644 0.7138059063 0.062417708 0.108595307
14 14 0.004920463 0.4021243224 0.720829502 0.271111765
15 15 0.361735030 0.2446397604 0.014402365 0.651462730
16 16 0.551963799 0.5182124697 0.155688312 0.085508447
17 17 0.654976624 0.6674429171 0.078464726 0.883908402
18 18 0.137046250 0.7913998954 0.844124627 0.280597467
19 19 0.193471635 0.2015982187 0.156952080 0.587406750
20 20 0.881816613 0.2206829412 0.644273973 0.031325495
21 21 0.015974925 0.6283761188 0.464664701 0.690404544
22 22 0.188228657 0.9531749445 0.526140009 0.105379215
23 23 0.088681881 0.8966324022 0.272559657 0.338925839
24 24 0.565564225 0.0786568980 0.616115056 0.501793555
25 25 0.883264024 0.5537378342 0.940248025 0.015593674
26 26 0.175526856 0.6696128728 0.864018623 0.138849922
27 27 0.072152113 0.8258232899 0.693274898 0.790408072
28 28 0.456256983 0.2879456531 0.962260917 0.344738215
29 29 0.933712926 0.0234263086 0.548796325 0.785795666
30 30 0.888064103 0.1113706253 0.021200851 0.348892384
31 31 0.069580676 0.6523396520 0.313577277 0.663605156
32 32 0.806092232 0.5036041433 0.574307983 0.198633342
33 33 0.949257809 0.6075049173 0.395444315 0.199935698
34 34 0.233545600 0.1940832301 0.288169791 0.428786108
35 35 0.595750775 0.3746601877 0.746830577 0.036646301
36 36 0.982634620 0.1835521521 0.510000831 0.098351384
37 37 0.118270901 0.7754267886 0.149177239 0.288551719
38 38 0.329725779 0.6546982563 0.090583064 0.485804268
39 39 0.025045791 0.1848958841 0.618410215 0.647245472
40 40 0.554672320 0.0005973703 0.846015700 0.750687035
41 41 0.950660877 0.9309914436 0.015844512 0.453066773
42 42 0.746608230 0.9659308153 0.021725258 0.272685102
43 43 0.019206457 0.1230470968 0.380367112 0.549695460
44 44 0.296595219 0.4762053381 0.026928285 0.910180914
45 45 0.686339484 0.4146721522 0.018669010 0.879647575
46 46 0.050407881 0.4293564399 0.786132085 0.791471829
47 47 0.513440507 0.0053965604 0.247257763 0.424315604
48 48 0.625499379 0.7788253236 0.463321284 0.515042219
49 49 0.725548951 0.7751243432 0.405205184 0.955069132
50 50 0.120046968 0.4020609419 0.041944529 0.500753322
51 51 0.005198592 0.5541655033 0.882458946 0.472243152
52 52 0.267637482 0.0990716070 0.614342373 0.882276396
53 53 0.339426865 0.0796072887 0.123243949 0.683783383
54 54 0.133924309 0.5379996671 0.796541746 0.307989638
55 55 0.307331378 0.8114126569 0.175435343 0.224575654
56 56 0.108531854 0.8698942723 0.215535779 0.740707801
57 57 0.758042989 0.3165158895 0.782920017 0.108276370
58 58 0.192873210 0.2176041028 0.462796648 0.719858833
59 59 0.522508319 0.0615535741 0.194959016 0.807160607
60 60 0.033809963 0.1650969910 0.367311198 0.798126610
61 61 0.656806023 0.7305918674 0.539253428 0.003001012
62 62 0.657445248 0.8239063487 0.676919465 0.064955021
63 63 0.079471620 0.1083707607 0.248867909 0.979508977
64 64 0.515082752 0.4570278882 0.806561476 0.043178570
65 65 0.012789760 0.8318734639 0.873228843 0.428629858
66 66 0.637243501 0.2269457169 0.809250126 0.576550005
67 67 0.173854540 0.8422606569 0.107787296 0.364891990
68 68 0.964293153 0.1036008853 0.598002952 0.699878295
69 69 0.158880327 0.9950064096 0.518066166 0.013612546
70 70 0.398211384 0.2122722516 0.257912886 0.205601375
71 71 0.024056164 0.4710086885 0.643505046 0.550677896
72 72 0.295100160 0.1494340737 0.878216476 0.914300596
73 73 0.953158544 0.0001105893 0.747205173 0.634195462
74 74 0.890661539 0.0411904832 0.749098084 0.859003738
75 75 0.187415506 0.6485780637 0.719565754 0.706176606
76 76 0.047403458 0.1006858206 0.332439194 0.595420982
77 77 0.264911317 0.1735050419 0.613031471 0.090466666
78 78 0.447927783 0.0218563643 0.218354955 0.413977401
79 79 0.841704479 0.1805881556 0.893164040 0.185389216
80 80 0.550790578 0.6073960383 0.357220705 0.215302692
81 81 0.230184596 0.0343396670 0.532604880 0.613264579
82 82 0.980423134 0.0281067949 0.285550123 0.983416513
83 83 0.463800704 0.9308310655 0.000600603 0.592185953
84 84 0.492274547 0.3743834812 0.044876648 0.933875799
85 85 0.060603475 0.8068036877 0.654841798 0.966169620
86 86 0.105166036 0.0529479169 0.776631706 0.713110954
87 87 0.174494283 0.4928633428 0.535967808 0.881722805
88 88 0.959867059 0.0251828259 0.409275848 0.610440125
89 89 0.578281808 0.2065009808 0.319648242 0.088305676
90 90 0.767718507 0.0796839484 0.120954998 0.195139451
91 91 0.037621635 0.5751435611 0.563041666 0.438113837
92 92 0.573316297 0.8478070809 0.172997600 0.604947700
93 93 0.770613692 0.1862094997 0.534193439 0.710333778
94 94 0.235562174 0.8743613510 0.065531308 0.081982669
95 95 0.003745653 0.8367713725 0.175692401 0.963800202
96 96 0.193971362 0.0188334094 0.171989316 0.981281073
97 97 0.586644845 0.6457188639 0.409790316 0.322051547
98 98 0.412581352 0.9700444618 0.568351826 0.071104909
99 99 0.024821827 0.5433256951 0.948164795 0.885831196
100 100 0.279113535 0.7399298260 0.436289226 0.137808192
p-value(PC5) p-value(PC6) p-value(PC7) p-value(PC8) p-value(PC9)
1 0.49716452 0.03492681 0.99242300 0.629669282 0.4881198
2 0.55673822 0.13427887 0.43566562 0.357739547 0.6738136
3 0.47722514 0.23467381 0.27008998 0.236846207 0.6405691
4 0.74463876 0.06174351 0.43702555 0.631698972 0.6824699
5 0.62495729 0.45462693 0.03860804 0.988432578 0.9720853
6 0.49001889 0.48019366 0.99492992 0.846104957 0.9126584
7 0.54199120 0.23009843 0.57530634 0.168822491 0.3014859
8 0.09660794 0.63140274 0.61462966 0.956233485 0.2646639
9 0.82903716 0.50881823 0.99059447 0.597688240 0.3244501
10 0.66225128 0.46171350 0.84735008 0.412729302 0.2867121
11 0.02600972 0.83510132 0.53321098 0.714207167 0.6296406
12 0.61581674 0.66849211 0.68944370 0.247257320 0.7944480
13 0.75329838 0.49588686 0.57672704 0.741998561 0.2142536
14 0.63373068 0.64125737 0.62772259 0.825347425 0.9262867
15 0.85781666 0.96517421 0.47001830 0.484508507 0.6844255
16 0.44917572 0.66330092 0.23923390 0.500059010 0.7328850
17 0.06192864 0.84126037 0.21671906 0.691199607 0.6337179
18 0.46222713 0.06858048 0.34142382 0.617457233 0.7251341
19 0.18335551 0.76777805 0.93069250 0.519886745 0.5098063
20 0.34923469 0.71342275 0.22655423 0.710153882 0.8226822
21 0.68798749 0.34648405 0.25767791 0.621032709 0.6808549
22 0.65833359 0.27604671 0.19532296 0.885931392 0.4474324
23 0.77182977 0.12628103 0.51753241 0.511911572 0.6427632
24 0.78499559 0.21584449 0.36283976 0.367409277 0.3089530
25 0.79561302 0.19544167 0.29688115 0.539269095 0.7003310
26 0.40037685 0.60289959 0.31265041 0.176470869 0.5998314
27 0.14207352 0.28594653 0.31226462 0.536449645 0.5392930
28 0.10831806 0.51558538 0.11927947 0.587854139 0.7056097
29 0.10168744 0.38868222 0.89326726 0.596298982 0.7246446
30 0.49365602 0.95612167 0.92301520 0.846927932 0.6371369
31 0.22637451 0.67796857 0.28138593 0.716476402 0.3528931
32 0.31020818 0.80331141 0.03774446 0.544542135 0.4397272
33 0.64447123 0.01187287 0.77256758 0.461484174 0.9245524
34 0.41150785 0.86837293 0.24047257 0.269227198 0.9105368
35 0.15395508 0.64070638 0.58835447 0.464759823 0.5875573
36 0.06801116 0.65097089 0.61587268 0.755828627 0.9590709
37 0.60618109 0.23953983 0.35799665 0.778996439 0.7580070
38 0.35783574 0.95906016 0.32429696 0.680106167 0.1649151
39 0.64731192 0.35788999 0.93892520 0.675503981 0.4047078
40 0.78391668 0.35467428 0.66758696 0.888734268 0.8791720
41 0.65597922 0.86977847 0.29676630 0.271005227 0.4414594
42 0.66036910 0.15410568 0.77508123 0.512879283 0.8099256
43 0.83576803 0.73850882 0.96408940 0.653876207 0.6829760
44 0.56579755 0.79731325 0.92582074 0.166208275 0.5646376
45 0.10631859 0.57625072 0.85077469 0.766260351 0.6864291
46 0.75115508 0.03918960 0.72574034 0.591515925 0.8477751
47 0.94066524 0.80579948 0.79727293 0.783348023 0.6211077
48 0.02524395 0.45141601 0.86808587 0.170750865 0.5242505
49 0.44576483 0.44828572 0.35783277 0.007041476 0.7574572
50 0.73902269 0.77127169 0.59970847 0.425557607 0.7568543
51 0.23300803 0.62081667 0.73635992 0.718363605 0.8506656
52 0.64309191 0.99759498 0.90556274 0.032210175 0.6673283
53 0.83777559 0.68789729 0.26532056 0.770808410 0.4657663
54 0.17139879 0.46809400 0.82585470 0.664727768 0.1543811
55 0.34004894 0.44229130 0.68812435 0.862060937 0.1375174
56 0.04378210 0.68071479 0.83514447 0.526347871 0.7718971
57 0.60160992 0.27758303 0.27946108 0.663438835 0.1793670
58 0.20734670 0.62374506 0.19723792 0.941056216 0.3531343
59 0.57002123 0.09466203 0.84274768 0.867111228 0.8156713
60 0.85072128 0.27248955 0.56730024 0.711371131 0.9787688
61 0.80017189 0.42689725 0.71893651 0.547206842 0.4650331
62 0.30417333 0.59945416 0.04505092 0.943494568 0.9555378
63 0.98512815 0.80533693 0.55254960 0.253843443 0.9966708
64 0.46292503 0.42766818 0.89983870 0.367092255 0.2030557
65 0.56825833 0.45060217 0.23180408 0.924912105 0.4907037
66 0.08505207 0.30089311 0.80408087 0.212483846 0.3907420
67 0.54814094 0.21531478 0.94711319 0.974694013 0.2676564
68 0.19303820 0.24541132 0.91506138 0.943992778 0.1162551
69 0.53397391 0.52371993 0.73781731 0.717090408 0.6579058
70 0.44547060 0.44711143 0.77857444 0.218819210 0.6128193
71 0.38781915 0.91387563 0.51509763 0.704463128 0.1969716
72 0.04156448 0.35487320 0.93154931 0.652628394 0.4957576
73 0.48099005 0.82921695 0.66330862 0.998193700 0.9350056
74 0.26121916 0.33713609 0.13684189 0.689175702 0.7878131
75 0.35580721 0.09414522 0.72656132 0.528749754 0.1453690
76 0.49431094 0.87923221 0.52632043 0.750057845 0.7842412
77 0.64428085 0.78174751 0.20422272 0.760016399 0.5977661
78 0.28278368 0.94950368 0.97708388 0.900872930 0.7604366
79 0.25883504 0.95681677 0.17875346 0.445727654 0.3095920
80 0.19774903 0.90798598 0.17479227 0.309867995 0.4184612
81 0.19428864 0.91212761 0.92564512 0.407083818 0.8710634
82 0.79780386 0.10452677 0.46987140 0.729271802 0.9849542
83 0.46466425 0.88616232 0.99512393 0.629609568 0.8945808
84 0.05067573 0.79343773 0.85966197 0.851812075 0.7859616
85 0.03259046 0.66258012 0.78165667 0.495129816 0.5658811
86 0.55403379 0.28889416 0.62559410 0.800161084 0.4895772
87 0.12451191 0.19341282 0.60296763 0.682345561 0.2835143
88 0.63795776 0.22750341 0.21177914 0.993102212 0.9113818
89 0.46621948 0.34418997 0.30240923 0.783686709 0.8780094
90 0.95121238 0.95033634 0.65533954 0.470412961 0.4102584
91 0.39482799 0.18362696 0.83759950 0.650919237 0.4639296
92 0.35360479 0.30155759 0.35308057 0.084953752 0.6569444
93 0.72355715 0.79285160 0.37827501 0.041702588 0.2418108
94 0.86598889 0.85564454 0.67073235 0.416790724 0.7189782
95 0.81587178 0.84047878 0.52232099 0.600694158 0.8360991
96 0.84988237 0.70152445 0.78028232 0.660928869 0.9214796
97 0.52622348 0.85550279 0.17609929 0.033179354 0.9389087
98 0.05670671 0.96605581 0.75148290 0.358173543 0.7040182
99 0.47756606 0.93606892 0.12679312 0.660947599 0.3624724
100 0.46756779 0.39666787 0.81689066 0.472689959 0.1173699
p-value(PC10)
1 9.747114e-01
2 5.565609e-01
3 8.992969e-01
4 4.062202e-01
5 7.548536e-01
6 1.454957e-01
7 3.617925e-01
8 3.535971e-02
9 5.365523e-01
10 5.419105e-01
11 8.910142e-01
12 9.861247e-01
13 7.058209e-01
14 6.198794e-01
15 5.306828e-02
16 5.476459e-01
17 7.737383e-01
18 6.907048e-01
19 1.415098e-02
20 5.564475e-01
21 7.941343e-01
22 9.970434e-01
23 9.268996e-01
24 1.620329e-01
25 2.947852e-01
26 7.020157e-01
27 3.846650e-01
28 4.188454e-01
29 2.882810e-01
30 2.048325e-02
31 9.551750e-01
32 4.176885e-01
33 5.509355e-01
34 1.908491e-01
35 3.307749e-01
36 1.863554e-01
37 8.856925e-01
38 9.481961e-01
39 2.012815e-01
40 3.123158e-02
41 9.310485e-01
42 8.959309e-01
43 1.571404e-01
44 9.643104e-01
45 4.057973e-01
46 3.897756e-01
47 3.750200e-02
48 8.184784e-01
49 7.595182e-01
50 5.987977e-01
51 1.141515e-01
52 4.945177e-01
53 1.631705e-01
54 8.652675e-01
55 7.120571e-01
56 5.490190e-01
57 9.535034e-01
58 5.472258e-01
59 1.806002e-01
60 5.779582e-01
61 9.665149e-01
62 9.375500e-01
63 2.511534e-01
64 7.883673e-01
65 7.350259e-01
66 7.917768e-02
67 5.941182e-01
68 7.534230e-02
69 9.743573e-01
70 7.467285e-01
71 5.906288e-01
72 2.909216e-01
73 8.351615e-06
74 9.679163e-02
75 8.569293e-01
76 4.344943e-01
77 6.207914e-01
78 1.667653e-01
79 5.019033e-01
80 9.122064e-01
81 3.802180e-04
82 9.459307e-02
83 8.033023e-01
84 8.109552e-02
85 2.564402e-01
86 1.573938e-02
87 5.996264e-01
88 9.561772e-02
89 2.327372e-02
90 1.600329e-02
91 6.052645e-01
92 7.041501e-01
93 1.730502e-01
94 2.163449e-01
95 6.500802e-01
96 4.919499e-02
97 6.408544e-01
98 8.420085e-01
99 2.063722e-01
100 8.012330e-01
Metabolite ID q-value(PC1) q-value(PC2) q-value(PC3) q-value(PC4)
1 1 0.9807048 0.97984289 0.5040870 0.9933500
2 2 0.4849284 0.97984289 0.6486524 0.9933500
3 3 0.2788439 0.97984289 0.9622609 0.9968418
4 4 0.8650595 0.97984289 0.9401727 0.6033073
5 5 0.2414997 0.97984289 0.9401727 0.9933500
6 6 0.8933879 0.63508554 0.5040870 0.6033073
7 7 0.7345648 0.53498738 0.9622609 0.9933500
8 8 0.9392867 0.37445894 0.9401727 0.9933500
9 9 0.1299648 0.97984289 0.8537298 0.9933500
10 10 0.2087149 0.97984289 0.8537298 0.9933500
11 11 0.4287392 0.97984289 0.9401727 0.9429524
12 12 0.2087149 0.97984289 0.7278498 0.9933500
13 13 0.9275758 0.97984289 0.5040870 0.6033073
14 14 0.1299648 0.89360961 0.9401727 0.9308120
15 15 0.6956443 0.63508554 0.3620876 0.9933500
16 16 0.8502099 0.97222018 0.6757400 0.6033073
17 17 0.8650595 0.97984289 0.5604623 0.9933500
18 18 0.4568208 0.97984289 0.9401727 0.9308120
19 19 0.4849284 0.61300817 0.6757400 0.9933500
20 20 0.9787489 0.61300817 0.9203914 0.6033073
21 21 0.2087149 0.97984289 0.8935860 0.9933500
22 22 0.4849284 0.97984289 0.9094268 0.6033073
23 23 0.3855734 0.97984289 0.8004716 0.9429524
24 24 0.8502099 0.49802468 0.9094268 0.9933500
25 25 0.9787489 0.97222018 0.9622609 0.5197891
26 26 0.4849284 0.97984289 0.9401727 0.6942496
27 27 0.3435815 0.97984289 0.9401727 0.9933500
28 28 0.7996564 0.71986413 0.9622609 0.9429524
29 29 0.9826346 0.35133494 0.9094268 0.9933500
30 30 0.9787489 0.53033631 0.3620876 0.9429524
31 31 0.3435815 0.97984289 0.8411796 0.9933500
32 32 0.9392867 0.96846951 0.9094268 0.8224055
33 33 0.9826346 0.97984289 0.8537298 0.8224055
34 34 0.5478190 0.61300817 0.8004716 0.9933500
35 35 0.8510725 0.87130276 0.9401727 0.6033073
36 36 0.9826346 0.61300817 0.9094268 0.6033073
37 37 0.4287392 0.97984289 0.6757400 0.9308120
38 38 0.6594516 0.97984289 0.6038871 0.9933500
39 39 0.2087149 0.61300817 0.9094268 0.9933500
40 40 0.8502099 0.02986852 0.9401727 0.9933500
41 41 0.9826346 0.97984289 0.3620876 0.9933500
42 42 0.9275758 0.97984289 0.3620876 0.9308120
43 43 0.2087149 0.53498738 0.8537298 0.9933500
44 44 0.6179067 0.95241068 0.3846898 0.9933500
45 45 0.8913500 0.90146120 0.3620876 0.9933500
46 46 0.2800438 0.91352434 0.9401727 0.9933500
47 47 0.8427554 0.17988535 0.7777122 0.9933500
48 48 0.8650595 0.97984289 0.8935860 0.9933500
49 49 0.9184164 0.97984289 0.8537298 0.9933500
50 50 0.4287392 0.89360961 0.4986294 0.9933500
51 51 0.1299648 0.97222018 0.9401727 0.9933500
52 52 0.5947500 0.53033631 0.9094268 0.9933500
53 53 0.6655429 0.49802468 0.6486524 0.9933500
54 54 0.4568208 0.97222018 0.9401727 0.9429524
55 55 0.6272069 0.97984289 0.6757400 0.8317617
56 56 0.4287392 0.97984289 0.7278498 0.9933500
57 57 0.9275758 0.77198997 0.9401727 0.6033073
58 58 0.4849284 0.61300817 0.8935860 0.9933500
59 59 0.8427554 0.47348903 0.7220704 0.9933500
60 60 0.2414997 0.61300817 0.8537298 0.9933500
61 61 0.8650595 0.97984289 0.9094268 0.3001012
62 62 0.8650595 0.97984289 0.9401659 0.6033073
63 63 0.3612346 0.53033631 0.7777122 0.9933500
64 64 0.8427554 0.95214143 0.9401727 0.6033073
65 65 0.2087149 0.97984289 0.9401727 0.9933500
66 66 0.8650595 0.61336680 0.9401727 0.9933500
67 67 0.4849284 0.97984289 0.6486524 0.9602421
68 68 0.9826346 0.53033631 0.9094268 0.9933500
69 69 0.4849284 0.99500641 0.9094268 0.5197891
70 70 0.7374285 0.61300817 0.7815542 0.8224055
71 71 0.2087149 0.95241068 0.9203914 0.9933500
72 72 0.6179067 0.61300817 0.9401727 0.9933500
73 73 0.9826346 0.01105893 0.9401727 0.9933500
74 74 0.9787489 0.37445894 0.9401727 0.9933500
75 75 0.4849284 0.97984289 0.9401727 0.9933500
76 76 0.2788439 0.53033631 0.8524082 0.9933500
77 77 0.5947500 0.61300817 0.9094268 0.6033073
78 78 0.7996564 0.35133494 0.7278498 0.9933500
79 79 0.9674764 0.61300817 0.9401727 0.8224055
80 80 0.8502099 0.97984289 0.8537298 0.8280873
81 81 0.5478190 0.37445894 0.9094268 0.9933500
82 82 0.9826346 0.35133494 0.8004716 0.9933500
83 83 0.7996564 0.97984289 0.0600603 0.9933500
84 84 0.8343636 0.87130276 0.4986294 0.9933500
85 85 0.3189657 0.97984289 0.9223124 0.9933500
86 86 0.4287392 0.44123264 0.9401727 0.9933500
87 87 0.4849284 0.96639871 0.9094268 0.9933500
88 88 0.9826346 0.35133494 0.8537298 0.9933500
89 89 0.8502099 0.61300817 0.8411796 0.6033073
90 90 0.9275758 0.49802468 0.6486524 0.8224055
91 91 0.2508109 0.97984289 0.9094268 0.9933500
92 92 0.8502099 0.97984289 0.6757400 0.9933500
93 93 0.9275758 0.61300817 0.9094268 0.9933500
94 94 0.5478190 0.97984289 0.5040870 0.6033073
95 95 0.1299648 0.97984289 0.6757400 0.9933500
96 96 0.4849284 0.35133494 0.6757400 0.9933500
97 97 0.8502099 0.97984289 0.8537298 0.9429524
98 98 0.7501479 0.97984289 0.9094268 0.6033073
99 99 0.2087149 0.97222018 0.9622609 0.9933500
100 100 0.6067686 0.97984289 0.8903862 0.6942496
q-value(PC5) q-value(PC6) q-value(PC7) q-value(PC8) q-value(PC9)
1 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
2 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
3 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
4 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
5 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
6 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
7 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
8 0.7737004 0.975814 0.9951239 0.9960765 0.9949032
9 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
10 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
11 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
12 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
13 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
14 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
15 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
16 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
17 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
18 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
19 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
20 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
21 0.8820352 0.975814 0.9951239 0.9675145 0.9949032
22 0.8600666 0.975814 0.9951239 0.9874825 0.9949032
23 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
24 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
25 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
26 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
27 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
28 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
29 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
30 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
31 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
32 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
33 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
34 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
35 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
36 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
37 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
38 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
39 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
40 0.8927721 0.975814 0.9951239 0.9874825 0.9949032
41 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
42 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
43 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
44 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
45 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
46 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
47 0.9598625 0.975814 0.9951239 0.9675145 0.9949032
48 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
49 0.8600666 0.975814 0.9951239 0.7041476 0.9949032
50 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
51 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
52 0.8600666 0.997595 0.9951239 0.9675145 0.9949032
53 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
54 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
55 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
56 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
57 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
58 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
59 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
60 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
61 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
62 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
63 0.9851282 0.975814 0.9951239 0.9675145 0.9966708
64 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
65 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
66 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
67 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
68 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
69 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
70 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
71 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
72 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
73 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
74 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
75 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
76 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
77 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
78 0.8600666 0.975814 0.9951239 0.9899703 0.9949032
79 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
80 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
81 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
82 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
83 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
84 0.7556796 0.975814 0.9951239 0.9853537 0.9949032
85 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
86 0.8600666 0.975814 0.9951239 0.9758062 0.9949032
87 0.8300794 0.975814 0.9951239 0.9675145 0.9949032
88 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
89 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
90 0.9608206 0.975814 0.9951239 0.9675145 0.9949032
91 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
92 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
93 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
94 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
95 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
96 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
97 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
98 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
99 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
100 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
q-value(PC10)
1 0.9946035121
2 0.9853831492
3 0.9946035121
4 0.9519213159
5 0.9946035121
6 0.6816038610
7 0.9519213159
8 0.3750199836
9 0.9853831492
10 0.9853831492
11 0.9946035121
12 0.9960855680
13 0.9946035121
14 0.9853831492
15 0.4422356750
16 0.9853831492
17 0.9946035121
18 0.9946035121
19 0.3200658925
20 0.9853831492
21 0.9946035121
22 0.9970434188
23 0.9946035121
24 0.6816038610
25 0.8188477238
26 0.9946035121
27 0.9519213159
28 0.9519213159
29 0.8188477238
30 0.3324816626
31 0.9946035121
32 0.9519213159
33 0.9853831492
34 0.6816038610
35 0.8939861810
36 0.6816038610
37 0.9946035121
38 0.9946035121
39 0.6879073220
40 0.3750199836
41 0.9946035121
42 0.9946035121
43 0.6816038610
44 0.9946035121
45 0.9519213159
46 0.9519213159
47 0.3750199836
48 0.9946035121
49 0.9946035121
50 0.9853831492
51 0.6007971333
52 0.9853831492
53 0.6816038610
54 0.9946035121
55 0.9946035121
56 0.9853831492
57 0.9946035121
58 0.9853831492
59 0.6816038610
60 0.9853831492
61 0.9946035121
62 0.9946035121
63 0.7770915940
64 0.9946035121
65 0.9946035121
66 0.5377312748
67 0.9853831492
68 0.5377312748
69 0.9946035121
70 0.9946035121
71 0.9853831492
72 0.8188477238
73 0.0008351615
74 0.5377312748
75 0.9946035121
76 0.9655427902
77 0.9853831492
78 0.6816038610
79 0.9853831492
80 0.9946035121
81 0.0190108981
82 0.5377312748
83 0.9946035121
84 0.5377312748
85 0.7770915940
86 0.3200658925
87 0.9853831492
88 0.5377312748
89 0.3324816626
90 0.3200658925
91 0.9853831492
92 0.9946035121
93 0.6816038610
94 0.6978866749
95 0.9946035121
96 0.4422356750
97 0.9946035121
98 0.9946035121
99 0.6879073220
100 0.9946035121
mseapca documentation built on May 1, 2019, 7:31 p.m.
R Package Documentation
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Description Usage Arguments Details Value Author(s) References Examples
Description
This function performs principal component analysis (PCA). In this function, data matrix is automatically scaled to zero mean and unit variance (autoscaling) for each metabolites. PC scores, factor loadings and the results of statistical test (p-value and q-value by Benjamini and Hochberg) are returned. In this function, factor loading is defined as a correlation coefficient between PC score and each metabolite levels.
Usage
1 |
Arguments
D |
dataframe of metabolite IDs and data matrix (metabolites * samples) |
Details
Blank must be set to missing values in data matrix. If standard deviation of metabolite levels is equal to zero, it is removed from PCA computation and the results of factor loadings are set to NA.
Value
list of PC scores, factor loadings, p-value and q-value (by Benjamini and Hochberg), and contribution ratios
Author(s)
Hiroyuki Yamamoto
References
Benjamini, Yoav and Hochberg, Yosef (1995). "Controlling the false discovery rate: a practical and powerful approach to multiple testing". Journal of the Royal Statistical Society, Series B (Methodological) 57 (1): 289-300.
Examples
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 | # --------------
# Sample data
# --------------
X <- matrix(runif(1000),nrow=100,ncol=10) # 100(metabolites)*10(samples)
M <- as.character(c(1:100)) # metabolite IDs
D <- data.frame(M,X) # dataframe of metabolite IDs and data matrix
# ---------------------------
# PCA for autoscaled data
# ---------------------------
A <- pca_scaled(D) # automatically scaled in pca_scaled function
# ---------
# Result
# ---------
A[["score"]] # PC score
A[["factor.loading"]] # factor loading
A[["p.value"]] # p-value of factor loading
A[["q.value"]] # q-value of factor loading
|
Example output
Loading required package: XML
PC score (PC1) PC score (PC2) PC score (PC3) PC score (PC4) PC score (PC5)
X1 -2.3516103 4.430179 -5.7566353 3.74186362 -1.314678982
X2 -5.6110382 3.859811 -2.3897620 -5.28827632 -0.005327863
X3 5.0881741 -4.010448 -5.8244445 -3.02079885 -0.844927386
X4 4.8067274 2.432981 0.7358249 5.65192956 -1.386052279
X5 0.6272150 -5.369643 -0.7186427 -0.02975301 -1.762402995
X6 -3.6364909 1.550733 2.9955384 1.51613161 -0.168443597
X7 -0.1371614 -2.588705 2.6107246 1.17927976 -0.347931958
X8 -3.0555710 -2.157531 4.5398183 -1.43315727 -4.631854390
X9 6.9192142 4.990746 3.6383635 -3.91850869 2.283473774
X10 -2.6494587 -3.138124 0.1692150 1.60128958 8.178145677
PC score (PC6) PC score (PC7) PC score (PC8) PC score (PC9) PC score (PC10)
X1 0.05450493 -2.0843406 3.1943400 2.1017053 -3.122502e-17
X2 1.14887292 0.9369788 -4.0767302 -0.1013663 -2.706169e-16
X3 -2.92285531 -0.5498972 0.4680440 -2.7752404 1.651457e-15
X4 2.18148108 0.4189789 -3.9021974 -2.2474831 8.153200e-16
X5 4.07721777 4.3269265 0.7483305 3.0414634 1.387779e-15
X6 -4.00285660 4.8029513 2.3293806 -2.3344426 -2.498002e-16
X7 -5.16450674 -1.9674867 -2.8921264 3.8193254 1.467576e-15
X8 2.23397657 -4.0789749 1.6740237 -1.9455820 6.591949e-16
X9 0.65924058 -0.1697410 2.1154270 1.5310159 -3.955170e-16
X10 1.73492480 -1.6353950 0.3415081 -1.0893958 2.040035e-15
Metabolite ID factor loading(PC1) factor loading(PC2) factor loading(PC3)
1 1 -0.044776091 -0.125057417 0.61401858
2 2 0.450222827 0.024642016 0.52953739
3 3 0.643099256 0.048805999 0.01896986
4 4 0.178544889 0.032123778 0.11768729
5 5 0.676159525 0.033123527 0.05986064
6 6 -0.141378368 0.403401425 -0.60683064
7 7 -0.306331914 -0.521385445 -0.03061141
8 8 -0.088560304 0.651814990 0.09364102
9 9 -0.826820298 -0.018956466 0.30956419
10 10 -0.750976206 0.132167201 -0.30522540
11 11 0.529580080 -0.076605005 0.05174051
12 12 -0.726601417 -0.054842440 0.43586011
13 13 -0.102008629 0.133168135 -0.60760875
14 14 0.805441983 0.298526291 -0.12978491
15 15 -0.323584219 0.405780146 0.74001613
16 16 0.214403581 -0.232395361 -0.48467757
17 17 -0.161902499 -0.155749585 -0.58054188
18 18 -0.504446530 -0.096246677 -0.07162361
19 19 0.448595273 -0.441393008 -0.48339073
20 20 0.054185503 0.425114842 -0.16721519
21 21 -0.732529421 0.175161191 -0.26197625
22 22 0.453336165 0.021415559 0.22812789
23 23 -0.565141758 0.047359842 -0.38453858
24 24 0.207277448 0.580240634 -0.18133640
25 25 0.053518040 -0.213470212 0.02733561
26 26 0.465153773 -0.154682311 -0.06240538
27 27 -0.590715338 -0.080136280 0.14311246
28 28 0.266752945 0.373340454 0.01725729
29 29 -0.030330549 -0.702718481 0.21607301
30 30 0.051305532 0.534602358 0.71083371
31 31 -0.595025412 -0.163208816 0.35537571
32 32 -0.089353544 0.240330582 -0.20273080
33 33 -0.023208928 0.185698537 0.30258308
34 34 0.414594194 0.448047170 -0.37317974
35 35 0.191689298 0.315422479 0.11733678
36 36 -0.007938960 0.457630720 0.23684426
37 37 -0.526106151 0.103772330 -0.49140977
38 38 0.344452257 0.162040318 -0.56240387
39 39 -0.697140881 0.456390204 -0.18017724
40 40 0.212979023 0.888134159 -0.07074584
41 41 0.022566516 -0.031578239 0.73313024
42 42 0.117442740 0.015578264 0.70887042
43 43 0.718622263 -0.520405080 0.31186311
44 44 -0.367186431 -0.255481580 0.69096021
45 45 -0.146491037 0.290991948 -0.72081624
46 46 0.631038990 -0.282309903 -0.09872481
47 47 -0.234977119 -0.800584674 0.40373306
48 48 -0.176606278 0.102168228 -0.26273689
49 49 -0.127516671 -0.103915162 -0.29666615
50 50 -0.523969704 -0.298564629 0.64989080
51 51 -0.802565720 0.213245378 0.05388928
52 52 0.388193246 0.550607420 0.18223272
53 53 0.338022848 -0.578757791 -0.52017309
54 54 0.507915022 0.221792266 0.09383125
55 55 -0.359679373 0.086863810 -0.46524072
56 56 -0.538193511 0.059689110 -0.42942259
57 57 -0.112003432 -0.353366466 -0.10023765
58 58 0.449132555 -0.427684570 0.26303420
59 59 0.230079570 0.609189711 -0.44726406
60 60 -0.670601929 -0.475243075 0.32004561
61 61 -0.160997242 0.125097383 0.22112579
62 62 0.160681121 -0.081029892 0.15109652
63 63 0.578968765 0.538399062 0.40248005
64 64 -0.234087504 0.266313341 -0.08913382
65 65 0.748312098 -0.077318410 -0.05814875
66 66 0.170720900 0.419950084 -0.08787539
67 67 -0.466746964 -0.072489121 -0.53914516
68 68 0.016327482 0.544574678 -0.19053815
69 69 -0.481439264 0.002282796 0.23247437
70 70 -0.300898671 -0.432184518 -0.39552362
71 71 0.700518659 -0.258397398 0.16759799
72 72 0.368243212 -0.491140871 -0.05584632
73 73 0.021423066 -0.927513800 -0.11715827
74 74 0.050108926 0.651690146 0.11625659
75 75 -0.454078357 -0.165075231 -0.13039297
76 76 -0.637470379 -0.548437721 0.34264425
77 77 -0.390233239 -0.467081075 -0.18289614
78 78 -0.271524113 -0.708384700 -0.42705597
79 79 0.072747439 0.460386120 -0.04895646
80 80 -0.215021491 -0.185753837 0.32646899
81 81 0.417310824 -0.669156455 -0.22466718
82 82 -0.008950141 -0.687240148 0.37506232
83 83 -0.262465334 0.031651775 -0.88797764
84 84 0.246551663 -0.315595735 -0.64309343
85 85 -0.610944880 0.089020421 -0.16196925
86 86 0.542528849 -0.625797880 -0.10320343
87 87 -0.466136419 0.246226864 -0.22287369
88 88 0.018352668 -0.696680419 -0.29421870
89 89 -0.200673125 0.437129255 0.35123547
90 90 -0.107416679 -0.578638683 -0.52288503
91 91 -0.660521163 -0.202297684 -0.20859413
92 92 0.203245132 0.069914652 0.46756689
93 93 0.106046884 0.455182615 0.22381942
94 94 0.412974829 -0.057625790 -0.60202867
95 95 -0.819064094 -0.075039925 0.46499655
96 96 -0.448147349 0.720140532 -0.46853472
97 97 -0.196359903 0.166496275 0.29391021
98 98 0.292239785 0.013696529 0.20582504
99 99 -0.697897176 0.218965296 0.02370942
100 100 0.379727786 -0.120629278 -0.27825893
factor loading(PC4) factor loading(PC5) factor loading(PC6)
1 0.088461928 -0.243859201 -0.667571786
2 -0.080746887 -0.211894277 0.507518614
3 -0.001443753 0.254911014 -0.413687241
4 -0.662745012 -0.118381690 -0.608840967
5 0.044703458 -0.176878843 -0.267683569
6 -0.562931120 -0.247797497 -0.253253175
7 0.123737982 -0.219672585 -0.417380768
8 0.188456183 -0.553962577 -0.173643250
9 -0.010636544 -0.078638950 -0.237487413
10 0.022734471 0.158307499 -0.263648499
11 0.353878386 -0.693937749 -0.075816556
12 -0.170366394 0.181487175 -0.155233411
13 -0.538112600 -0.114257857 -0.244561599
14 -0.385609857 0.172477408 -0.168717834
15 -0.163643610 0.065275519 0.015924400
16 0.569796873 -0.270806732 -0.157789835
17 -0.053220935 -0.608501736 -0.072953729
18 0.378647063 -0.263357124 0.596729925
19 0.195968090 0.457812701 0.107388493
20 0.677594877 0.331617519 0.133352964
21 -0.144509519 0.145687293 0.333404585
22 0.542251690 -0.160241964 -0.381971221
23 0.338352576 0.105471885 0.516622615
24 -0.241320764 0.099259923 -0.429162573
25 0.734295602 -0.094267280 0.446833355
26 -0.502464715 -0.299584396 0.188040734
27 -0.096712983 -0.498961648 0.374776851
28 0.334542576 -0.538466354 -0.233815465
29 -0.098883191 -0.547102483 -0.306723508
30 -0.331839519 -0.245789862 0.020066741
31 -0.157639837 0.420417757 0.150582645
32 0.444000716 -0.357691484 -0.090656180
33 -0.442852482 0.167117007 0.753360467
34 0.282644501 -0.292881634 0.060392157
35 0.663032321 -0.486452749 -0.168992546
36 -0.551582725 0.597707398 -0.163887557
37 0.372906046 0.186371163 0.409803408
38 -0.250131921 0.326074899 0.018721917
39 0.165737282 0.165704262 -0.326040152
40 -0.115500152 0.099768090 0.328104298
41 0.268575699 0.161406278 0.059742620
42 0.384445914 0.159236418 -0.486298024
43 -0.215598733 -0.075506481 -0.121308256
44 -0.041129660 0.207155776 0.093469119
45 0.055186013 -0.541034591 0.201724165
46 -0.096212863 -0.115277409 0.656574704
47 0.285274419 -0.027144453 0.089490636
48 0.234109447 0.696475569 0.269521144
49 0.020548500 0.272769647 0.271318262
50 0.241890333 0.121062680 0.105735735
51 -0.257703472 -0.415027205 0.178963470
52 0.053973462 0.167803722 -0.001099438
53 -0.147738816 -0.074573061 0.145731270
54 0.359223649 0.469103125 -0.260039009
55 0.421894954 0.337613800 -0.274775646
56 -0.120257694 -0.645595024 -0.149238641
57 -0.538519592 -0.188697787 -0.380845697
58 0.130251928 -0.436399715 0.177488656
59 0.088853324 -0.204956542 0.556651287
60 -0.093087421 0.068563101 0.384590379
61 0.829382463 -0.092127961 0.283754119
62 -0.603048151 -0.361872946 -0.189797225
63 -0.009368147 0.006798874 0.089707261
64 0.646992354 0.262961434 -0.283300960
65 0.282736205 -0.205873706 0.269987830
66 -0.201569207 -0.570475406 0.364164179
67 0.321577520 0.216418902 -0.429608857
68 -0.139904895 -0.448984330 -0.405175580
69 0.743993364 -0.223936513 -0.229427835
70 -0.437907182 -0.272939295 0.271993889
71 0.215080866 -0.307254470 0.039432396
72 0.039237223 -0.650794949 0.327976338
73 0.172244815 0.252809176 -0.078555219
74 -0.064725919 0.393014557 0.339532464
75 0.136853716 -0.327376006 0.557371290
76 0.191857997 -0.245429028 -0.055377648
77 -0.562570431 0.167211764 -0.100790236
78 -0.291406261 -0.377060498 -0.023096348
79 0.455936101 -0.394822043 -0.019748607
80 -0.429619050 -0.444782881 0.042138294
81 0.182778135 0.447863310 -0.040235308
82 -0.007581458 -0.093238875 0.543362109
83 -0.193514624 -0.261976508 -0.052181938
84 0.030255888 0.630478149 -0.095288986
85 0.015469017 -0.673989162 -0.158145293
86 -0.133503392 0.213314615 0.372660813
87 -0.054228767 0.518684264 0.448648038
88 -0.184209038 0.170364152 -0.419494119
89 -0.565687973 -0.261097160 0.334900546
90 0.447102971 -0.022314020 -0.022715103
91 0.277197715 0.302959034 -0.457561522
92 0.186998309 0.328792880 0.363698978
93 -0.134844070 0.128473468 0.095564387
94 0.575100937 0.061494237 0.066281490
95 -0.016553014 -0.084779638 -0.073316820
96 0.008557851 -0.068952095 0.139106664
97 0.349607829 -0.228083103 -0.066347154
98 0.592458317 -0.618339601 0.015521081
99 0.052334557 -0.254720390 0.029250652
100 -0.503607393 -0.260335861 0.301837568
factor loading(PC7) factor loading(PC8) factor loading(PC9)
1 0.003463811 -0.1745123276 0.248848278
2 0.278622102 0.3261365115 -0.152619277
3 0.386367740 0.4119477847 -0.169060983
4 0.277830431 0.1734948170 -0.148380556
5 0.658025802 -0.0052881120 0.012763079
6 -0.002317765 0.0707044204 0.039991475
7 -0.202213336 0.4715966844 -0.363749107
8 -0.182087404 0.0200155665 -0.390418952
9 0.004299749 0.1906989099 0.347989664
10 0.070126668 0.2921513875 0.374226121
11 -0.224343602 0.1329746009 0.174526711
12 -0.144977568 -0.4037334101 -0.094814417
13 -0.201477556 -0.1196414121 0.430504837
14 0.175489282 -0.0803580756 -0.033735887
15 0.258954698 0.2508513780 -0.147425226
16 0.410046271 0.2422707745 0.123998752
17 0.428427110 0.1441223728 0.172483779
18 -0.336711100 -0.1806583546 0.127715908
19 -0.031715309 -0.2314918633 -0.236950007
20 0.420270537 0.1349309659 -0.081600765
21 -0.395702611 -0.1788545871 -0.149170107
22 0.446939231 -0.0522883751 0.271809147
23 0.232762691 -0.2358064159 0.167967468
24 -0.322881012 0.3199836141 0.358557608
25 -0.366984647 0.2211174642 -0.139685329
26 0.356011488 0.4642584055 0.189604732
27 0.356276412 0.2226170917 0.221104783
28 -0.524890499 0.1957381063 -0.137128024
29 -0.048908938 0.1914089480 0.127950997
30 0.035236768 0.0703225348 -0.170774166
31 0.378074100 0.1318806876 -0.329251674
32 0.660208063 -0.2183211794 -0.276261073
33 0.105123124 -0.2637786436 -0.034531499
34 0.409064015 0.3870089117 0.040966127
35 0.195480982 0.2619224339 0.195890689
36 0.181458898 0.1130551621 0.018717009
37 0.325971848 0.1020875046 0.112020507
38 0.348092825 -0.1495363577 0.475422339
39 0.027941713 0.1517902450 0.296965973
40 -0.155678703 -0.0509967535 -0.055405438
41 -0.367065684 0.3856888065 0.275257114
42 0.103935525 -0.2352814085 -0.087559374
43 -0.016420703 -0.1624474221 0.148133233
44 0.033949621 0.4741502807 0.207760852
45 0.068538335 -0.1081070371 -0.146447306
46 -0.127424770 0.1938581517 -0.069929476
47 0.093488042 -0.1000359873 -0.178816788
48 -0.060524833 0.4697281284 0.229142603
49 -0.326076796 0.7858485703 -0.112281604
50 0.189667455 -0.2845424829 0.112567936
51 0.122335677 0.1309716709 -0.068588911
52 -0.043252143 -0.6750629805 -0.155805965
53 0.389926273 0.1059548003 -0.261353234
54 -0.080121641 0.1570865484 -0.486015327
55 -0.145620570 0.0633110161 -0.503927352
56 -0.075796490 -0.2280163564 -0.105440075
57 0.379474399 0.1577218344 -0.461529129
58 0.445235880 0.0269653285 0.329096107
59 0.072262944 -0.0609753538 0.084873271
60 0.206372621 0.1343431169 0.009706611
61 -0.130695851 0.2169121790 -0.261767815
62 -0.642698904 0.0258483181 0.020333963
63 0.214095245 -0.3986363706 0.001521939
64 -0.045884504 0.3201840482 -0.440119231
65 0.415999050 -0.0343664546 -0.247418985
66 -0.090295643 0.4320047084 -0.305458612
67 -0.024190977 0.0115699997 -0.388179099
68 -0.038887837 -0.0256201116 -0.528555423
69 0.121638790 -0.1315848638 0.160453421
70 0.102286588 0.4266679215 -0.183003558
71 0.234079449 0.1376830217 0.445472226
72 -0.031322456 -0.1630656942 -0.244632682
73 -0.157786035 -0.0008257378 0.029738010
74 0.504672077 -0.1451081507 -0.097933615
75 0.127030636 -0.2267288053 -0.495430328
76 0.228031081 -0.1157996391 0.099615201
77 0.439103193 0.1110667789 -0.190659147
78 0.010477088 -0.0454087469 0.110867390
79 -0.462105116 -0.2727910809 0.358116465
80 -0.465852487 -0.3579260474 -0.288738112
81 -0.034030184 -0.2955351950 0.059148929
82 -0.259037408 0.1257302364 0.006878409
83 -0.002229071 0.1745422796 -0.048304181
84 0.064421217 -0.0680574054 -0.098805076
85 0.100833054 0.2449781486 -0.207112209
86 -0.176558660 -0.0921330288 -0.248041725
87 0.188006082 0.1484413193 0.376531790
88 0.432603960 0.0031533057 -0.040577936
89 0.363103536 -0.0998764242 -0.055941875
90 -0.161722850 -0.2587325588 0.293629704
91 0.074654916 0.1639131800 0.262392353
92 0.329130776 0.5706218880 -0.160928811
93 -0.313164878 0.6504657475 0.408005976
94 -0.154132130 -0.2897305582 0.130675801
95 0.230180392 -0.1891646518 -0.075352517
96 0.101481017 -0.1589600667 0.035941450
97 0.464610500 -0.6723429245 0.027949284
98 -0.115121419 0.3258585881 0.137898447
99 0.516029200 -0.1589508212 0.323114705
100 -0.084303733 -0.2574525064 0.527197643
factor loading(PC10)
1 -0.011562029
2 -0.211987331
3 -0.046133743
4 -0.296054785
5 -0.113518490
6 -0.495295492
7 0.323547593
8 -0.666414943
9 -0.222562444
10 -0.219715356
11 0.049946470
12 -0.006343244
13 -0.137025817
14 -0.179436025
15 -0.625553703
16 0.216680304
17 -0.104569910
18 0.144363309
19 0.741265088
20 -0.212046816
21 -0.094961763
22 0.001351582
23 0.033454735
24 -0.478279231
25 0.368466219
26 -0.138868574
27 -0.309199812
28 -0.288510102
29 0.373100032
30 -0.713575369
31 -0.020500058
32 -0.289196960
33 -0.214945155
34 -0.450957140
35 -0.343752307
36 -0.455048820
37 -0.052398480
38 -0.023695069
39 -0.441670461
40 -0.677866489
41 0.031552060
42 0.047682692
43 0.483199513
44 0.016319587
45 -0.296309412
46 0.306051685
47 0.660826803
48 0.083562346
49 0.111303179
50 0.190132320
51 -0.531139792
52 -0.245315144
53 0.477147993
54 0.061827803
55 0.134011975
56 -0.215955537
57 0.021265198
58 0.216902142
59 -0.460374912
60 0.200840499
61 -0.015311081
62 -0.028571872
63 -0.400709194
64 -0.097672872
65 0.122973893
66 -0.579426660
67 0.192524766
68 -0.585504854
69 -0.011723966
70 0.117385409
71 0.194313193
72 0.371212079
73 0.962404979
74 -0.553710559
75 0.065686434
76 0.279304906
77 0.178976217
78 0.473604148
79 -0.241260677
80 0.040199096
81 0.900465498
82 0.556747215
83 -0.090660461
84 0.576458579
85 -0.396646910
86 0.733617094
87 -0.189709316
88 0.555326441
89 -0.703257529
90 0.732399176
91 0.186837185
92 -0.137834584
93 -0.467516537
94 0.428741574
95 -0.164329467
96 -0.633603777
97 -0.168918716
98 -0.072606251
99 -0.437240500
100 0.091630393
Metabolite ID p-value(PC1) p-value(PC2) p-value(PC3) p-value(PC4)
1 1 0.902248440 0.7306752546 0.058962988 0.807996755
2 2 0.191662197 0.9461283108 0.115452935 0.824513350
3 3 0.044874077 0.8934908265 0.958518356 0.996841798
4 4 0.621647322 0.9298017049 0.746095159 0.036757016
5 5 0.031824970 0.9276217315 0.869523067 0.902406373
6 6 0.696842583 0.2476833603 0.062845926 0.090214935
7 7 0.389319350 0.1222173885 0.933100254 0.733429587
8 8 0.807786575 0.0411385058 0.796947012 0.602084026
9 9 0.003174949 0.9585476278 0.384075586 0.976735192
10 10 0.012299948 0.7158818584 0.391122397 0.950294041
11 11 0.115418140 0.8334064698 0.887120137 0.315765821
12 12 0.017301963 0.8803923378 0.207973512 0.637953267
13 13 0.779163644 0.7138059063 0.062417708 0.108595307
14 14 0.004920463 0.4021243224 0.720829502 0.271111765
15 15 0.361735030 0.2446397604 0.014402365 0.651462730
16 16 0.551963799 0.5182124697 0.155688312 0.085508447
17 17 0.654976624 0.6674429171 0.078464726 0.883908402
18 18 0.137046250 0.7913998954 0.844124627 0.280597467
19 19 0.193471635 0.2015982187 0.156952080 0.587406750
20 20 0.881816613 0.2206829412 0.644273973 0.031325495
21 21 0.015974925 0.6283761188 0.464664701 0.690404544
22 22 0.188228657 0.9531749445 0.526140009 0.105379215
23 23 0.088681881 0.8966324022 0.272559657 0.338925839
24 24 0.565564225 0.0786568980 0.616115056 0.501793555
25 25 0.883264024 0.5537378342 0.940248025 0.015593674
26 26 0.175526856 0.6696128728 0.864018623 0.138849922
27 27 0.072152113 0.8258232899 0.693274898 0.790408072
28 28 0.456256983 0.2879456531 0.962260917 0.344738215
29 29 0.933712926 0.0234263086 0.548796325 0.785795666
30 30 0.888064103 0.1113706253 0.021200851 0.348892384
31 31 0.069580676 0.6523396520 0.313577277 0.663605156
32 32 0.806092232 0.5036041433 0.574307983 0.198633342
33 33 0.949257809 0.6075049173 0.395444315 0.199935698
34 34 0.233545600 0.1940832301 0.288169791 0.428786108
35 35 0.595750775 0.3746601877 0.746830577 0.036646301
36 36 0.982634620 0.1835521521 0.510000831 0.098351384
37 37 0.118270901 0.7754267886 0.149177239 0.288551719
38 38 0.329725779 0.6546982563 0.090583064 0.485804268
39 39 0.025045791 0.1848958841 0.618410215 0.647245472
40 40 0.554672320 0.0005973703 0.846015700 0.750687035
41 41 0.950660877 0.9309914436 0.015844512 0.453066773
42 42 0.746608230 0.9659308153 0.021725258 0.272685102
43 43 0.019206457 0.1230470968 0.380367112 0.549695460
44 44 0.296595219 0.4762053381 0.026928285 0.910180914
45 45 0.686339484 0.4146721522 0.018669010 0.879647575
46 46 0.050407881 0.4293564399 0.786132085 0.791471829
47 47 0.513440507 0.0053965604 0.247257763 0.424315604
48 48 0.625499379 0.7788253236 0.463321284 0.515042219
49 49 0.725548951 0.7751243432 0.405205184 0.955069132
50 50 0.120046968 0.4020609419 0.041944529 0.500753322
51 51 0.005198592 0.5541655033 0.882458946 0.472243152
52 52 0.267637482 0.0990716070 0.614342373 0.882276396
53 53 0.339426865 0.0796072887 0.123243949 0.683783383
54 54 0.133924309 0.5379996671 0.796541746 0.307989638
55 55 0.307331378 0.8114126569 0.175435343 0.224575654
56 56 0.108531854 0.8698942723 0.215535779 0.740707801
57 57 0.758042989 0.3165158895 0.782920017 0.108276370
58 58 0.192873210 0.2176041028 0.462796648 0.719858833
59 59 0.522508319 0.0615535741 0.194959016 0.807160607
60 60 0.033809963 0.1650969910 0.367311198 0.798126610
61 61 0.656806023 0.7305918674 0.539253428 0.003001012
62 62 0.657445248 0.8239063487 0.676919465 0.064955021
63 63 0.079471620 0.1083707607 0.248867909 0.979508977
64 64 0.515082752 0.4570278882 0.806561476 0.043178570
65 65 0.012789760 0.8318734639 0.873228843 0.428629858
66 66 0.637243501 0.2269457169 0.809250126 0.576550005
67 67 0.173854540 0.8422606569 0.107787296 0.364891990
68 68 0.964293153 0.1036008853 0.598002952 0.699878295
69 69 0.158880327 0.9950064096 0.518066166 0.013612546
70 70 0.398211384 0.2122722516 0.257912886 0.205601375
71 71 0.024056164 0.4710086885 0.643505046 0.550677896
72 72 0.295100160 0.1494340737 0.878216476 0.914300596
73 73 0.953158544 0.0001105893 0.747205173 0.634195462
74 74 0.890661539 0.0411904832 0.749098084 0.859003738
75 75 0.187415506 0.6485780637 0.719565754 0.706176606
76 76 0.047403458 0.1006858206 0.332439194 0.595420982
77 77 0.264911317 0.1735050419 0.613031471 0.090466666
78 78 0.447927783 0.0218563643 0.218354955 0.413977401
79 79 0.841704479 0.1805881556 0.893164040 0.185389216
80 80 0.550790578 0.6073960383 0.357220705 0.215302692
81 81 0.230184596 0.0343396670 0.532604880 0.613264579
82 82 0.980423134 0.0281067949 0.285550123 0.983416513
83 83 0.463800704 0.9308310655 0.000600603 0.592185953
84 84 0.492274547 0.3743834812 0.044876648 0.933875799
85 85 0.060603475 0.8068036877 0.654841798 0.966169620
86 86 0.105166036 0.0529479169 0.776631706 0.713110954
87 87 0.174494283 0.4928633428 0.535967808 0.881722805
88 88 0.959867059 0.0251828259 0.409275848 0.610440125
89 89 0.578281808 0.2065009808 0.319648242 0.088305676
90 90 0.767718507 0.0796839484 0.120954998 0.195139451
91 91 0.037621635 0.5751435611 0.563041666 0.438113837
92 92 0.573316297 0.8478070809 0.172997600 0.604947700
93 93 0.770613692 0.1862094997 0.534193439 0.710333778
94 94 0.235562174 0.8743613510 0.065531308 0.081982669
95 95 0.003745653 0.8367713725 0.175692401 0.963800202
96 96 0.193971362 0.0188334094 0.171989316 0.981281073
97 97 0.586644845 0.6457188639 0.409790316 0.322051547
98 98 0.412581352 0.9700444618 0.568351826 0.071104909
99 99 0.024821827 0.5433256951 0.948164795 0.885831196
100 100 0.279113535 0.7399298260 0.436289226 0.137808192
p-value(PC5) p-value(PC6) p-value(PC7) p-value(PC8) p-value(PC9)
1 0.49716452 0.03492681 0.99242300 0.629669282 0.4881198
2 0.55673822 0.13427887 0.43566562 0.357739547 0.6738136
3 0.47722514 0.23467381 0.27008998 0.236846207 0.6405691
4 0.74463876 0.06174351 0.43702555 0.631698972 0.6824699
5 0.62495729 0.45462693 0.03860804 0.988432578 0.9720853
6 0.49001889 0.48019366 0.99492992 0.846104957 0.9126584
7 0.54199120 0.23009843 0.57530634 0.168822491 0.3014859
8 0.09660794 0.63140274 0.61462966 0.956233485 0.2646639
9 0.82903716 0.50881823 0.99059447 0.597688240 0.3244501
10 0.66225128 0.46171350 0.84735008 0.412729302 0.2867121
11 0.02600972 0.83510132 0.53321098 0.714207167 0.6296406
12 0.61581674 0.66849211 0.68944370 0.247257320 0.7944480
13 0.75329838 0.49588686 0.57672704 0.741998561 0.2142536
14 0.63373068 0.64125737 0.62772259 0.825347425 0.9262867
15 0.85781666 0.96517421 0.47001830 0.484508507 0.6844255
16 0.44917572 0.66330092 0.23923390 0.500059010 0.7328850
17 0.06192864 0.84126037 0.21671906 0.691199607 0.6337179
18 0.46222713 0.06858048 0.34142382 0.617457233 0.7251341
19 0.18335551 0.76777805 0.93069250 0.519886745 0.5098063
20 0.34923469 0.71342275 0.22655423 0.710153882 0.8226822
21 0.68798749 0.34648405 0.25767791 0.621032709 0.6808549
22 0.65833359 0.27604671 0.19532296 0.885931392 0.4474324
23 0.77182977 0.12628103 0.51753241 0.511911572 0.6427632
24 0.78499559 0.21584449 0.36283976 0.367409277 0.3089530
25 0.79561302 0.19544167 0.29688115 0.539269095 0.7003310
26 0.40037685 0.60289959 0.31265041 0.176470869 0.5998314
27 0.14207352 0.28594653 0.31226462 0.536449645 0.5392930
28 0.10831806 0.51558538 0.11927947 0.587854139 0.7056097
29 0.10168744 0.38868222 0.89326726 0.596298982 0.7246446
30 0.49365602 0.95612167 0.92301520 0.846927932 0.6371369
31 0.22637451 0.67796857 0.28138593 0.716476402 0.3528931
32 0.31020818 0.80331141 0.03774446 0.544542135 0.4397272
33 0.64447123 0.01187287 0.77256758 0.461484174 0.9245524
34 0.41150785 0.86837293 0.24047257 0.269227198 0.9105368
35 0.15395508 0.64070638 0.58835447 0.464759823 0.5875573
36 0.06801116 0.65097089 0.61587268 0.755828627 0.9590709
37 0.60618109 0.23953983 0.35799665 0.778996439 0.7580070
38 0.35783574 0.95906016 0.32429696 0.680106167 0.1649151
39 0.64731192 0.35788999 0.93892520 0.675503981 0.4047078
40 0.78391668 0.35467428 0.66758696 0.888734268 0.8791720
41 0.65597922 0.86977847 0.29676630 0.271005227 0.4414594
42 0.66036910 0.15410568 0.77508123 0.512879283 0.8099256
43 0.83576803 0.73850882 0.96408940 0.653876207 0.6829760
44 0.56579755 0.79731325 0.92582074 0.166208275 0.5646376
45 0.10631859 0.57625072 0.85077469 0.766260351 0.6864291
46 0.75115508 0.03918960 0.72574034 0.591515925 0.8477751
47 0.94066524 0.80579948 0.79727293 0.783348023 0.6211077
48 0.02524395 0.45141601 0.86808587 0.170750865 0.5242505
49 0.44576483 0.44828572 0.35783277 0.007041476 0.7574572
50 0.73902269 0.77127169 0.59970847 0.425557607 0.7568543
51 0.23300803 0.62081667 0.73635992 0.718363605 0.8506656
52 0.64309191 0.99759498 0.90556274 0.032210175 0.6673283
53 0.83777559 0.68789729 0.26532056 0.770808410 0.4657663
54 0.17139879 0.46809400 0.82585470 0.664727768 0.1543811
55 0.34004894 0.44229130 0.68812435 0.862060937 0.1375174
56 0.04378210 0.68071479 0.83514447 0.526347871 0.7718971
57 0.60160992 0.27758303 0.27946108 0.663438835 0.1793670
58 0.20734670 0.62374506 0.19723792 0.941056216 0.3531343
59 0.57002123 0.09466203 0.84274768 0.867111228 0.8156713
60 0.85072128 0.27248955 0.56730024 0.711371131 0.9787688
61 0.80017189 0.42689725 0.71893651 0.547206842 0.4650331
62 0.30417333 0.59945416 0.04505092 0.943494568 0.9555378
63 0.98512815 0.80533693 0.55254960 0.253843443 0.9966708
64 0.46292503 0.42766818 0.89983870 0.367092255 0.2030557
65 0.56825833 0.45060217 0.23180408 0.924912105 0.4907037
66 0.08505207 0.30089311 0.80408087 0.212483846 0.3907420
67 0.54814094 0.21531478 0.94711319 0.974694013 0.2676564
68 0.19303820 0.24541132 0.91506138 0.943992778 0.1162551
69 0.53397391 0.52371993 0.73781731 0.717090408 0.6579058
70 0.44547060 0.44711143 0.77857444 0.218819210 0.6128193
71 0.38781915 0.91387563 0.51509763 0.704463128 0.1969716
72 0.04156448 0.35487320 0.93154931 0.652628394 0.4957576
73 0.48099005 0.82921695 0.66330862 0.998193700 0.9350056
74 0.26121916 0.33713609 0.13684189 0.689175702 0.7878131
75 0.35580721 0.09414522 0.72656132 0.528749754 0.1453690
76 0.49431094 0.87923221 0.52632043 0.750057845 0.7842412
77 0.64428085 0.78174751 0.20422272 0.760016399 0.5977661
78 0.28278368 0.94950368 0.97708388 0.900872930 0.7604366
79 0.25883504 0.95681677 0.17875346 0.445727654 0.3095920
80 0.19774903 0.90798598 0.17479227 0.309867995 0.4184612
81 0.19428864 0.91212761 0.92564512 0.407083818 0.8710634
82 0.79780386 0.10452677 0.46987140 0.729271802 0.9849542
83 0.46466425 0.88616232 0.99512393 0.629609568 0.8945808
84 0.05067573 0.79343773 0.85966197 0.851812075 0.7859616
85 0.03259046 0.66258012 0.78165667 0.495129816 0.5658811
86 0.55403379 0.28889416 0.62559410 0.800161084 0.4895772
87 0.12451191 0.19341282 0.60296763 0.682345561 0.2835143
88 0.63795776 0.22750341 0.21177914 0.993102212 0.9113818
89 0.46621948 0.34418997 0.30240923 0.783686709 0.8780094
90 0.95121238 0.95033634 0.65533954 0.470412961 0.4102584
91 0.39482799 0.18362696 0.83759950 0.650919237 0.4639296
92 0.35360479 0.30155759 0.35308057 0.084953752 0.6569444
93 0.72355715 0.79285160 0.37827501 0.041702588 0.2418108
94 0.86598889 0.85564454 0.67073235 0.416790724 0.7189782
95 0.81587178 0.84047878 0.52232099 0.600694158 0.8360991
96 0.84988237 0.70152445 0.78028232 0.660928869 0.9214796
97 0.52622348 0.85550279 0.17609929 0.033179354 0.9389087
98 0.05670671 0.96605581 0.75148290 0.358173543 0.7040182
99 0.47756606 0.93606892 0.12679312 0.660947599 0.3624724
100 0.46756779 0.39666787 0.81689066 0.472689959 0.1173699
p-value(PC10)
1 9.747114e-01
2 5.565609e-01
3 8.992969e-01
4 4.062202e-01
5 7.548536e-01
6 1.454957e-01
7 3.617925e-01
8 3.535971e-02
9 5.365523e-01
10 5.419105e-01
11 8.910142e-01
12 9.861247e-01
13 7.058209e-01
14 6.198794e-01
15 5.306828e-02
16 5.476459e-01
17 7.737383e-01
18 6.907048e-01
19 1.415098e-02
20 5.564475e-01
21 7.941343e-01
22 9.970434e-01
23 9.268996e-01
24 1.620329e-01
25 2.947852e-01
26 7.020157e-01
27 3.846650e-01
28 4.188454e-01
29 2.882810e-01
30 2.048325e-02
31 9.551750e-01
32 4.176885e-01
33 5.509355e-01
34 1.908491e-01
35 3.307749e-01
36 1.863554e-01
37 8.856925e-01
38 9.481961e-01
39 2.012815e-01
40 3.123158e-02
41 9.310485e-01
42 8.959309e-01
43 1.571404e-01
44 9.643104e-01
45 4.057973e-01
46 3.897756e-01
47 3.750200e-02
48 8.184784e-01
49 7.595182e-01
50 5.987977e-01
51 1.141515e-01
52 4.945177e-01
53 1.631705e-01
54 8.652675e-01
55 7.120571e-01
56 5.490190e-01
57 9.535034e-01
58 5.472258e-01
59 1.806002e-01
60 5.779582e-01
61 9.665149e-01
62 9.375500e-01
63 2.511534e-01
64 7.883673e-01
65 7.350259e-01
66 7.917768e-02
67 5.941182e-01
68 7.534230e-02
69 9.743573e-01
70 7.467285e-01
71 5.906288e-01
72 2.909216e-01
73 8.351615e-06
74 9.679163e-02
75 8.569293e-01
76 4.344943e-01
77 6.207914e-01
78 1.667653e-01
79 5.019033e-01
80 9.122064e-01
81 3.802180e-04
82 9.459307e-02
83 8.033023e-01
84 8.109552e-02
85 2.564402e-01
86 1.573938e-02
87 5.996264e-01
88 9.561772e-02
89 2.327372e-02
90 1.600329e-02
91 6.052645e-01
92 7.041501e-01
93 1.730502e-01
94 2.163449e-01
95 6.500802e-01
96 4.919499e-02
97 6.408544e-01
98 8.420085e-01
99 2.063722e-01
100 8.012330e-01
Metabolite ID q-value(PC1) q-value(PC2) q-value(PC3) q-value(PC4)
1 1 0.9807048 0.97984289 0.5040870 0.9933500
2 2 0.4849284 0.97984289 0.6486524 0.9933500
3 3 0.2788439 0.97984289 0.9622609 0.9968418
4 4 0.8650595 0.97984289 0.9401727 0.6033073
5 5 0.2414997 0.97984289 0.9401727 0.9933500
6 6 0.8933879 0.63508554 0.5040870 0.6033073
7 7 0.7345648 0.53498738 0.9622609 0.9933500
8 8 0.9392867 0.37445894 0.9401727 0.9933500
9 9 0.1299648 0.97984289 0.8537298 0.9933500
10 10 0.2087149 0.97984289 0.8537298 0.9933500
11 11 0.4287392 0.97984289 0.9401727 0.9429524
12 12 0.2087149 0.97984289 0.7278498 0.9933500
13 13 0.9275758 0.97984289 0.5040870 0.6033073
14 14 0.1299648 0.89360961 0.9401727 0.9308120
15 15 0.6956443 0.63508554 0.3620876 0.9933500
16 16 0.8502099 0.97222018 0.6757400 0.6033073
17 17 0.8650595 0.97984289 0.5604623 0.9933500
18 18 0.4568208 0.97984289 0.9401727 0.9308120
19 19 0.4849284 0.61300817 0.6757400 0.9933500
20 20 0.9787489 0.61300817 0.9203914 0.6033073
21 21 0.2087149 0.97984289 0.8935860 0.9933500
22 22 0.4849284 0.97984289 0.9094268 0.6033073
23 23 0.3855734 0.97984289 0.8004716 0.9429524
24 24 0.8502099 0.49802468 0.9094268 0.9933500
25 25 0.9787489 0.97222018 0.9622609 0.5197891
26 26 0.4849284 0.97984289 0.9401727 0.6942496
27 27 0.3435815 0.97984289 0.9401727 0.9933500
28 28 0.7996564 0.71986413 0.9622609 0.9429524
29 29 0.9826346 0.35133494 0.9094268 0.9933500
30 30 0.9787489 0.53033631 0.3620876 0.9429524
31 31 0.3435815 0.97984289 0.8411796 0.9933500
32 32 0.9392867 0.96846951 0.9094268 0.8224055
33 33 0.9826346 0.97984289 0.8537298 0.8224055
34 34 0.5478190 0.61300817 0.8004716 0.9933500
35 35 0.8510725 0.87130276 0.9401727 0.6033073
36 36 0.9826346 0.61300817 0.9094268 0.6033073
37 37 0.4287392 0.97984289 0.6757400 0.9308120
38 38 0.6594516 0.97984289 0.6038871 0.9933500
39 39 0.2087149 0.61300817 0.9094268 0.9933500
40 40 0.8502099 0.02986852 0.9401727 0.9933500
41 41 0.9826346 0.97984289 0.3620876 0.9933500
42 42 0.9275758 0.97984289 0.3620876 0.9308120
43 43 0.2087149 0.53498738 0.8537298 0.9933500
44 44 0.6179067 0.95241068 0.3846898 0.9933500
45 45 0.8913500 0.90146120 0.3620876 0.9933500
46 46 0.2800438 0.91352434 0.9401727 0.9933500
47 47 0.8427554 0.17988535 0.7777122 0.9933500
48 48 0.8650595 0.97984289 0.8935860 0.9933500
49 49 0.9184164 0.97984289 0.8537298 0.9933500
50 50 0.4287392 0.89360961 0.4986294 0.9933500
51 51 0.1299648 0.97222018 0.9401727 0.9933500
52 52 0.5947500 0.53033631 0.9094268 0.9933500
53 53 0.6655429 0.49802468 0.6486524 0.9933500
54 54 0.4568208 0.97222018 0.9401727 0.9429524
55 55 0.6272069 0.97984289 0.6757400 0.8317617
56 56 0.4287392 0.97984289 0.7278498 0.9933500
57 57 0.9275758 0.77198997 0.9401727 0.6033073
58 58 0.4849284 0.61300817 0.8935860 0.9933500
59 59 0.8427554 0.47348903 0.7220704 0.9933500
60 60 0.2414997 0.61300817 0.8537298 0.9933500
61 61 0.8650595 0.97984289 0.9094268 0.3001012
62 62 0.8650595 0.97984289 0.9401659 0.6033073
63 63 0.3612346 0.53033631 0.7777122 0.9933500
64 64 0.8427554 0.95214143 0.9401727 0.6033073
65 65 0.2087149 0.97984289 0.9401727 0.9933500
66 66 0.8650595 0.61336680 0.9401727 0.9933500
67 67 0.4849284 0.97984289 0.6486524 0.9602421
68 68 0.9826346 0.53033631 0.9094268 0.9933500
69 69 0.4849284 0.99500641 0.9094268 0.5197891
70 70 0.7374285 0.61300817 0.7815542 0.8224055
71 71 0.2087149 0.95241068 0.9203914 0.9933500
72 72 0.6179067 0.61300817 0.9401727 0.9933500
73 73 0.9826346 0.01105893 0.9401727 0.9933500
74 74 0.9787489 0.37445894 0.9401727 0.9933500
75 75 0.4849284 0.97984289 0.9401727 0.9933500
76 76 0.2788439 0.53033631 0.8524082 0.9933500
77 77 0.5947500 0.61300817 0.9094268 0.6033073
78 78 0.7996564 0.35133494 0.7278498 0.9933500
79 79 0.9674764 0.61300817 0.9401727 0.8224055
80 80 0.8502099 0.97984289 0.8537298 0.8280873
81 81 0.5478190 0.37445894 0.9094268 0.9933500
82 82 0.9826346 0.35133494 0.8004716 0.9933500
83 83 0.7996564 0.97984289 0.0600603 0.9933500
84 84 0.8343636 0.87130276 0.4986294 0.9933500
85 85 0.3189657 0.97984289 0.9223124 0.9933500
86 86 0.4287392 0.44123264 0.9401727 0.9933500
87 87 0.4849284 0.96639871 0.9094268 0.9933500
88 88 0.9826346 0.35133494 0.8537298 0.9933500
89 89 0.8502099 0.61300817 0.8411796 0.6033073
90 90 0.9275758 0.49802468 0.6486524 0.8224055
91 91 0.2508109 0.97984289 0.9094268 0.9933500
92 92 0.8502099 0.97984289 0.6757400 0.9933500
93 93 0.9275758 0.61300817 0.9094268 0.9933500
94 94 0.5478190 0.97984289 0.5040870 0.6033073
95 95 0.1299648 0.97984289 0.6757400 0.9933500
96 96 0.4849284 0.35133494 0.6757400 0.9933500
97 97 0.8502099 0.97984289 0.8537298 0.9429524
98 98 0.7501479 0.97984289 0.9094268 0.6033073
99 99 0.2087149 0.97222018 0.9622609 0.9933500
100 100 0.6067686 0.97984289 0.8903862 0.6942496
q-value(PC5) q-value(PC6) q-value(PC7) q-value(PC8) q-value(PC9)
1 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
2 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
3 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
4 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
5 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
6 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
7 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
8 0.7737004 0.975814 0.9951239 0.9960765 0.9949032
9 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
10 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
11 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
12 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
13 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
14 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
15 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
16 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
17 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
18 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
19 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
20 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
21 0.8820352 0.975814 0.9951239 0.9675145 0.9949032
22 0.8600666 0.975814 0.9951239 0.9874825 0.9949032
23 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
24 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
25 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
26 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
27 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
28 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
29 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
30 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
31 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
32 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
33 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
34 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
35 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
36 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
37 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
38 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
39 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
40 0.8927721 0.975814 0.9951239 0.9874825 0.9949032
41 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
42 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
43 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
44 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
45 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
46 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
47 0.9598625 0.975814 0.9951239 0.9675145 0.9949032
48 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
49 0.8600666 0.975814 0.9951239 0.7041476 0.9949032
50 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
51 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
52 0.8600666 0.997595 0.9951239 0.9675145 0.9949032
53 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
54 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
55 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
56 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
57 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
58 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
59 0.8600666 0.975814 0.9951239 0.9853537 0.9949032
60 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
61 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
62 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
63 0.9851282 0.975814 0.9951239 0.9675145 0.9966708
64 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
65 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
66 0.7737004 0.975814 0.9951239 0.9675145 0.9949032
67 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
68 0.8600666 0.975814 0.9951239 0.9936766 0.9949032
69 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
70 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
71 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
72 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
73 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
74 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
75 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
76 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
77 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
78 0.8600666 0.975814 0.9951239 0.9899703 0.9949032
79 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
80 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
81 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
82 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
83 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
84 0.7556796 0.975814 0.9951239 0.9853537 0.9949032
85 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
86 0.8600666 0.975814 0.9951239 0.9758062 0.9949032
87 0.8300794 0.975814 0.9951239 0.9675145 0.9949032
88 0.8600666 0.975814 0.9951239 0.9981937 0.9949032
89 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
90 0.9608206 0.975814 0.9951239 0.9675145 0.9949032
91 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
92 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
93 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
94 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
95 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
96 0.8927721 0.975814 0.9951239 0.9675145 0.9949032
97 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
98 0.7556796 0.975814 0.9951239 0.9675145 0.9949032
99 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
100 0.8600666 0.975814 0.9951239 0.9675145 0.9949032
q-value(PC10)
1 0.9946035121
2 0.9853831492
3 0.9946035121
4 0.9519213159
5 0.9946035121
6 0.6816038610
7 0.9519213159
8 0.3750199836
9 0.9853831492
10 0.9853831492
11 0.9946035121
12 0.9960855680
13 0.9946035121
14 0.9853831492
15 0.4422356750
16 0.9853831492
17 0.9946035121
18 0.9946035121
19 0.3200658925
20 0.9853831492
21 0.9946035121
22 0.9970434188
23 0.9946035121
24 0.6816038610
25 0.8188477238
26 0.9946035121
27 0.9519213159
28 0.9519213159
29 0.8188477238
30 0.3324816626
31 0.9946035121
32 0.9519213159
33 0.9853831492
34 0.6816038610
35 0.8939861810
36 0.6816038610
37 0.9946035121
38 0.9946035121
39 0.6879073220
40 0.3750199836
41 0.9946035121
42 0.9946035121
43 0.6816038610
44 0.9946035121
45 0.9519213159
46 0.9519213159
47 0.3750199836
48 0.9946035121
49 0.9946035121
50 0.9853831492
51 0.6007971333
52 0.9853831492
53 0.6816038610
54 0.9946035121
55 0.9946035121
56 0.9853831492
57 0.9946035121
58 0.9853831492
59 0.6816038610
60 0.9853831492
61 0.9946035121
62 0.9946035121
63 0.7770915940
64 0.9946035121
65 0.9946035121
66 0.5377312748
67 0.9853831492
68 0.5377312748
69 0.9946035121
70 0.9946035121
71 0.9853831492
72 0.8188477238
73 0.0008351615
74 0.5377312748
75 0.9946035121
76 0.9655427902
77 0.9853831492
78 0.6816038610
79 0.9853831492
80 0.9946035121
81 0.0190108981
82 0.5377312748
83 0.9946035121
84 0.5377312748
85 0.7770915940
86 0.3200658925
87 0.9853831492
88 0.5377312748
89 0.3324816626
90 0.3200658925
91 0.9853831492
92 0.9946035121
93 0.6816038610
94 0.6978866749
95 0.9946035121
96 0.4422356750
97 0.9946035121
98 0.9946035121
99 0.6879073220
100 0.9946035121
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