Bioconductor-mirror/DMRforPairs: DMRforPairs: identifying Differentially Methylated Regions between unique samples using array based methylation profiles
Version 1.13.0

DMRforPairs (formerly DMR2+) allows researchers to compare n>=2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishes DMRforPairs from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance.

Getting started

Package details

AuthorMartin Rijlaarsdam [aut, cre], Yvonne vd Zwan [aut], Lambert Dorssers [aut], Leendert Looijenga [aut]
Bioconductor views Annotation DNAMethylation DifferentialMethylation Microarray ReportWriting Visualization
MaintainerMartin Rijlaarsdam <[email protected]>
LicenseGPL (>= 2)
Version1.13.0
URL http://www.martinrijlaarsdam.nl http://www.erasmusmc.nl/pathologie/research/lepo/3898639/
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("devtools")
library(devtools)
install_github("Bioconductor-mirror/DMRforPairs")
Bioconductor-mirror/DMRforPairs documentation built on May 29, 2017, 3:16 a.m.