Bioconductor-mirror/DrugVsDisease: Comparison of disease and drug profiles using Gene set Enrichment Analysis

This package generates ranked lists of differential gene expression for either disease or drug profiles. Input data can be downloaded from Array Express or GEO, or from local CEL files. Ranked lists of differential expression and associated p-values are calculated using Limma. Enrichment scores (Subramanian et al. PNAS 2005) are calculated to a reference set of default drug or disease profiles, or a set of custom data supplied by the user. Network visualisation of significant scores are output in Cytoscape format.

Getting started

Package details

AuthorC. Pacini
Bioconductor views Clustering GeneExpression Microarray
Maintainerj. Saez-Rodriguez <[email protected]>
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
Bioconductor-mirror/DrugVsDisease documentation built on Aug. 6, 2017, 8:03 p.m.