We developed SRGnet to analyze synergistic regulatory mechanisms in transcriptome profiles that act to enhance the overall cell response to combination of mutations, drugs or environmental exposure. This package can be used to identify regulatory modules downstream of synergistic response genes, prioritize synergistic regulatory genes that may be potential intervention targets, and contextualize gene perturbation experiments.
|Author||Isar Nassiri [aut, cre], Matthew McCall [aut, cre]|
|Bioconductor views||Regression Software StatisticalMethod|
|Maintainer||Isar Nassiri <[email protected]>|
|Package repository||View on GitHub|
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