Bioconductor-mirror/TargetScore: TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
Version 1.15.0

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Getting started

Package details

AuthorYue Li
Bioconductor views miRNA
MaintainerYue Li <[email protected]>
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
Bioconductor-mirror/TargetScore documentation built on June 1, 2017, 3:22 a.m.