This function allow to visualize the histogram of raw p-value distribution generated by limma analysis.
The histogram of raw p-value distribution will show if raw p-values are uniform in the non significant range and therefore the BH correction can be applied.
BH is the most used method for the correction of type I errors in microarray analysis. However, it has some limitation due to the initial hypotheses: The gene expressions are independent from each other. The raw distribution of p values should be uniform in the non significant range.
Raffaele A Calogero
To know more see limma package help
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