A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija (2019) <doi:10.1186/s13059-019-1874-1>, and Choudhary and Satija (2022) <doi:10.1186/s13059-021-02584-9> for more details.
Package details |
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Maintainer | |
License | GPL-3 | file LICENSE |
Version | 0.4.1 |
URL | https://github.com/satijalab/sctransform |
Package repository | View on GitHub |
Installation |
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