README.md

In JEFworks/badger: Bayesian approach for detecting copy number alterations from single cell RNA-seq data

Overview of BADGER

The badger package implements a hierarchical Bayesian approach for inferring copy number alterations and loss of heterozygosity events from single-cell RNA-seq data based on allele and gene expression patterns.

Installation

require(devtools)
devtools::install_github('JEFworks/badger', build_vignettes = FALSE)

Sample analyses and images

Contributing

We welcome any bug reports, enhancement requests, and other contributions. To submit a bug report or enhancement request, or for general discussions or troubleshooting, please use the badger GitHub issues tracker. For more substantial contributions, please fork this repo, push your changes to your fork, and submit a pull request with a good commit message.

badger is created and maintained by Jean Fan of the Kharchenko Lab at the Department of Biomedical Informatics at Harvard Medical School.

JEFworks/badger documentation built on May 7, 2019, 7:40 a.m.