data-dds: Gene expression data

Description Usage Format Author(s) References


The object contains the gene expression data after differential gene expression analysis performed with DESeq2 R/Bioconductor package. The preprocessing of the RNA-Seq data included read alignment to the human reference genome (GRCh 37.1 / hg 19; STAR version 2.3.0), and read counting done with htseq-count (default mode union).




"DESeqDataSet" object with 136 CLL samples and 63677 features.


Sascha Dietrich


Love MI, Huber W, and Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15(12):550

Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, and Gingeras TR. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013;29(1):15-21

Anders S, Pyl PT, and Huber W. HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics. 2015;31(2):166-9

MalgorzataOles/pace documentation built on Nov. 18, 2017, 7:51 a.m.