BN: Toy Boolean model

In SPIDDOR/SPIDDOR: SPIDDOR

Description

A small Boolean network used as an example to illustrate the SPIDDOR functions. This network is adapted from Ruiz-Cerda et al.

Usage

data("Example_network")

Details

The data consists of a list named BN with 12 nodes describing some of the mechanism by which an antigen is presented by the APCs to T cells. In this process, antigenic particles must be captured and presented to T cells with the appropriate concomitant signals. The components of the BN list are described in more detail in read.Boolean.functions. Additionally, the Boolean functions of the network appear as a argument of this list, in order to read them with read.Boolean.functions instead of using a text file.

Source

Ruiz-Cerda ML, Irurzun-Arana I, Gonzalez-Garcia I, Hu C, Zhou H, et al (2016). Towards patient stratification and treatment in the autoimmune disease lupus erythematosus using a systems pharmacology approach. Eur J Pharm Sci.

Examples

data("Example_network")

# The network is stored in a variable called 'BN'
print(BN)

SPIDDOR/SPIDDOR documentation built on May 9, 2019, 11:42 a.m.