Optimal design for a Pharmocokinetic study

dprior | Prior density of theta |

est_dLdt | Estimate the gradient of the loss function w.r.t design |

imp_samp | Importance sampler with prior proposal |

loglik | Log-likelihood |

MSE | Mean Square Error |

rprior | Random draw from the prior of theta |

sgd_L | Run a Stochastic Gradient Descent algorithm for PK model |

utility | Calculate an estimate of the utility of a design |

y_t | Generate a value from PK model in RDP paper (+ additive... |

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