README.md

In Yafei611/idr3c: Differential gene expression analysis by integrating data from multiple sources

3-components IDR

idr3c is a semi-parametric model to determine differential expressions using information across different sources. It can be applied to the integration of RNA-seq and microarray data. By incorporating both the significance of differential expression and the consistency across platforms, our method effectively detects differential expressions with moderate but consistent signals.

Installing

The package can be installed from github. R package devtools is required.

library(devtools)
install_github("Yafei611/idr3c")
library(idr3c)

Example

x = expr
plot(x[,1],x[,2],xlim=c(-8,8),ylim=c(-8,8),cex = .4);
idr.out = IDR.3component(x = x)

Citation

Please cite the following paper: A semi-parametric statistical model for integrating gene expression profiles across different platforms: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-015-0847-y

Yafei611/idr3c documentation built on May 9, 2019, 11:07 p.m.