##' @title Loops over values of alpha -- **needs tidying up**
##'
##' @description Removes false positives for various values of the tolerance parameter alpha
##' @param data As for remove_false_pos()
##' @param alpha_vec Vector of alpha (tolerance) values over which to run remove_false_pos().
##' @param aT Total number of control species.
##' @return List consisting of:
##' ***: list of dataframes, one for each result of the corresponding
##' value of alpha;
##' num_zeroed: vector corresponding to the number of reads set to zero for each value of alphavec;
##' num_mock_sp_left: ***
##' num_samp_with_mock: ***
##' @author Andrew Edwards
##' @export
change_alpha = function(data, alpha_vec = c(0.01, seq(0.1, 1, 0.1)), aT = 4) {
N <- length(alpha_vec)
out_list = list() # Will be a list of dataframes, each being the result for
# the corresponding value of alpha_vec
num_zeroed = vector(length = N)
num_mock_sp_left = vector(length = N)
num_samp_rem_with_mock_sp = vector(length = N)
for(i in 1:N)
{
out_list[[i]] = remove_false_pos(data, aT = aT, alpha = alpha_vec[i])
diff = which_set_to_zero(data, out_list[[i]])
num_zeroed[i] = sum(as.vector(diff) > 0,
na.rm = TRUE) # CHECK doesn't give warnings
mock_sp_out = out_list[[i]][2:dim(out_list[[i]])[1], 2:(aT + 1)]
# just control species in non-mock samples. **assumes one mock sample
# num_mock_sp_zeroed[i] = sum(as.vector(mock_sp_rem) > 0)
num_mock_sp_left[i] = sum(as.vector(mock_sp_out > 0))
num_samp_rem_with_mock_sp[i] = sum(rowSums(mock_sp_out) > 0)
}
return(list(out_list = out_list,
num_zeroed = num_zeroed,
num_mock_sp_left = num_mock_sp_left,
num_samp_rem_with_mock_sp = num_samp_rem_with_mock_sp))
}
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