README.md
In bozdaglab/miRDriver: miRDriver: A Tool to Infer Copy Number Derived miRNA-Gene Networks in Cancer
miRDriver
R package miRDriver identifies frequently aberrated regions using GISTIC and computes differentially expressed genes between the two patient groups as frequently aberrated group and not frequently aberrated group. Utilizing copy number aberration, DNA methylation, gene expression, transcription factor expression and miRNA expression datasets, miRDriver applies a LASSO-based method to select miRNAs-target gene interactions. We tested miRDriver on breast cancer and ovarian cancer data from the Cancer Genome Atlas (TCGA) database.
Please follow the R folder for the source codes.
bozdaglab/miRDriver documentation built on Feb. 1, 2022, 1:11 p.m.
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miRDriver
R package miRDriver identifies frequently aberrated regions using GISTIC and computes differentially expressed genes between the two patient groups as frequently aberrated group and not frequently aberrated group. Utilizing copy number aberration, DNA methylation, gene expression, transcription factor expression and miRNA expression datasets, miRDriver applies a LASSO-based method to select miRNAs-target gene interactions. We tested miRDriver on breast cancer and ovarian cancer data from the Cancer Genome Atlas (TCGA) database.
Please follow the R folder for the source codes.
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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