The KSEAapp R package offers a panel of functions for kinase activity inference on an input phosphoproteomics dataset using the Kinase-Substrate Enrichment Analysis (KSEA) method originally described by Casado et al. (see references below).
For details on its usage and features, please read the Overview.Rmd file within the vignettes folder.
Note: if you are interested in performing KSEA through a user-friendly online interface, please visit this link, or get details from our other GitHub site.
Elements found in 2, 5, 6, and 7 are key components for building the R package but are not crucial for understanding the basis of the KSEA calculations.
There are 2 options for installing the KSEAapp package within the R console:
(1) Via CRAN
This gives access to the newest CRAN release version.
install.packages("KSEAapp")
(2) Via GitHub
This gives access to the newest development version.
install.packages("devtools") # this installs the devtools R package
devtools::install_github("casecpb/KSEAapp")
References:
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