cnfoley/Sun-et-al-2021-protein-coding-variants-in-human-disease: Computing and predicting gains in power owing to allelic heterogenity between population cohorts

Simulation protocol to asssess impact of allelic enrichment on meta-analyses for 2 studies across a range of minor allele frequencies (in study 1) and allelic enrichment values (for study 2). Summary genetic association data are simulated, parameterised by observed association and disease prevelance data.

Getting started

Package details

AuthorChristopher Neal Foley and Benjamin B Sun
MaintainerChristopher Foley <chris.neal.foley@gmail.com> and Benjamin Sun <bbsun92@outlook.com>
LicenseGPL-3
Version0.1.0
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("cnfoley/Sun-et-al-2021-protein-coding-variants-in-human-disease")
cnfoley/Sun-et-al-2021-protein-coding-variants-in-human-disease documentation built on Dec. 19, 2021, 5:19 p.m.