README.md

In dkornai/QuieScore: Uses Single Cell Gene Expression Data to Score Tumor Quiescence

QuieScore

The QuieScore R package is meant to help identify tumour quiescence, and aid in the classification of quiescence subtypes, as described in Wiecek et al, Genome Biol 2023

Authors

Daniel Kornai, Maria Secrier

Installation

The package can be installed by using "devtools".

How to run

For a sample script and input data, please see the sampleScript folder.

Output

q_score_raw - the raw G0 arrest scores (anything above 0 would be arrested in G0, and if you want to be more stringent you can use a cut-off of 1.5 or 3)

q_score_normalised - aligns the scores with respect to TCGA samples from the same cancer type (NB this is only suitable when looking at bulk cancer samples, and only for cancers that are profiled in TCGA)

Copyright

This code is free and is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY. See the GNU General Public License for more details.

dkornai/QuieScore documentation built on July 3, 2024, 2:29 p.m.