README.md

In dungtsa/BayesianPredictiveFutility: Interim Analysis for Futility Using Bayesian Predictive Probability

BayesianPredictiveFutility

The tool provides futility interim analysis plan using the Bayesian predictive design in single arm early phase II clinical trial. It also generates statistical plan so clinicians could easily incorporate it into the clinical trial protocol. (reference: Application of Bayesian predictive probability for interim analysis in single-arm early phase II trial. Chen et al; submitted).

Features

• The shiny applictaion provides futility interim analysis plan for the Bayesian predictive design design in single arm early phase II clinical trial and generates a statistical plan to be easily incorporated into the clinical trial protocol.

Installation

Simply run the following from an R console:

if (!require("devtools"))
  install.packages("devtools")
devtools::install_github("dungtsa/BayesianPredictiveFutility",force = TRUE)

Getting Started

library("BayesianPredictiveFutility")
Bayesian_Predictive_App()

Procedure of BayesianPredictiveFutility R Shiny App

Example of two-stage case

Example of three-stage case

Example of multi-stage case

dungtsa/BayesianPredictiveFutility documentation built on April 10, 2022, 7:48 p.m.