README.md

In mammmals/XLmap: Map Protein Cross-Link Sites To Protein Structure Contact Maps

XLmap

http://bioinformatics.oxfordjournals.org/content/early/2015/10/06/bioinformatics.btv519

Motivation: Chemical cross-linking with mass spectrometry (XL-MS) provides structural information for proteins and protein complexes in the form of crosslinked residue proximity and distance constraints between reactive residues. Utilizing spatial information derived from cross-linked residues can therefore assist with structural modeling of proteins. Selection of computationally derived model structures of proteins remains a major challenge in structural biology. The comparison of site interactions resulting from XL-MS with protein structure contact maps can assist the selection of structural models.

mammmals/XLmap documentation built on May 21, 2019, 11:22 a.m.