cats
is a fork of the R package CATS
developed by Anders Albrechtsen <aalbrechtsen@bio.ku.dk> for power estimation in two-stage genome-wide association designs. See the vignette for code examples.
# install.packages("devtools")
devtools::install_github("nanxstats/cats")
The method for power analysis implemented in CATS
is based on Skol et al. 2006, but more generalized so that the ratio between cases and controls may vary between stages. The allele frequencies, disease prevalence, and relative risk can also vary.
The changes made to the original R package CATS
are only for fixing the package build and check issues (under R 3.6.0 as of May 2019), for example:
This package is forked and modified from these resources. They are also available as archives under bin/
:
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