These data frames describe the compounds used in each of plates tested in a series of cytotoxicity experiments on cell-lines from the pediatric cancer Ewings' sarcoma. Data frames describe plates from several different experiments or sets of experiments:
Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the ES1 cell line.
Follow up experiments combining BMN 673 and SN-38 with several additional mechanistic classes in the ES1 cell line.
Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the ES8 cell line.
Follow up experiments combining BMN 673 and SN-38 with several additional mechanistic classes in the ES8 cell line.
Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the EW8 cell line.
1 | data(ewings)
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Data frames containing the following columns:
The number of a plate run in a particular experiment
The compound drugged in decreasing concentration across the plate (DMSO if none)
The compound drugged in decreasing concentration down the plate (DMSO if none)
The average base-10 logarithm of CellTiter-Glo intensity in positive control wells on the plate, normalized to intensity in negative control wells on the same plate
The date on which the experiment using that plate was run
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