es1plates: Plate Information from Ewings-Sarcoma Experiments

Description Usage Format

Description

These data frames describe the compounds used in each of plates tested in a series of cytotoxicity experiments on cell-lines from the pediatric cancer Ewings' sarcoma. Data frames describe plates from several different experiments or sets of experiments:

es1plates

Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the ES1 cell line.

es1extplates

Follow up experiments combining BMN 673 and SN-38 with several additional mechanistic classes in the ES1 cell line.

es8plates

Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the ES8 cell line.

es8extplates

Follow up experiments combining BMN 673 and SN-38 with several additional mechanistic classes in the ES8 cell line.

ew8plates

Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the EW8 cell line.

Usage

1
data(ewings)

Format

Data frames containing the following columns:

plate

The number of a plate run in a particular experiment

compound1

The compound drugged in decreasing concentration across the plate (DMSO if none)

compound2

The compound drugged in decreasing concentration down the plate (DMSO if none)

posmean

The average base-10 logarithm of CellTiter-Glo intensity in positive control wells on the plate, normalized to intensity in negative control wells on the same plate

date

The date on which the experiment using that plate was run


nathanieltwarog/braidrm documentation built on May 23, 2019, 12:19 p.m.