PICS is a statistical approach to improve prediction of cancer subgroups and identification of key genes and pathways by integrating information from biological pathway databases.
To install the development version of PICS, it's easiest to use the 'devtools' package.
#install.packages("devtools")
library(devtools)
install_github("sunny-zq/PICS")
The R package vignette will provide a good start point for the genetic analysis using PICS package, including the overview of PICS package and the example command lines:
library(PICS)
vignette("PICS-example")
The following two help pages will also provide quick references for PICS package and the example command lines:
package?PICS
class?PICS
Wei W, Sun Z, da Silveira WA, Yu Z, Lawson A, Hardiman G, Kelemen LE, and Chung D (2017), "PICS: Pathway-guided identification of cancer subgroups."
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