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A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.
Package details |
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| Author | Junwei Han [aut, cre, cph], Ji Li [aut], Jiashuo Wu [aut] |
| Maintainer | Junwei Han <hanjunwei1981@163.com> |
| License | GPL (>= 2) |
| Version | 0.1.2 |
| Package repository | View on CRAN |
| Installation |
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