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GenTwoArmsTrialSize: Generalized Two Arms Clinical Trial Sample Size Calculation
Two arms clinical trials required sample size is calculated in the comprehensive parametric context. The calculation is based on the type of endpoints(continuous/binary/time-to-event/ordinal), design (parallel/crossover), hypothesis tests (equality/noninferiority/superiority/equivalence), trial arms noncompliance rates and expected loss of follow-up. Methods are described in: Chow SC, Shao J, Wang H, Lokhnygina Y (2017) <doi:10.1201/9781315183084>, Wittes, J (2002) <doi:10.1093/epirev/24.1.39>, Sato, T (2000) <doi:10.1002/1097-0258(20001015)19:19%3C2689::aid-sim555%3E3.0.co;2-0>, Lachin J M, Foulkes, M A (1986) <doi:10.2307/2531201>, Whitehead J(1993) <doi:10.1002/sim.4780122404>, Julious SA (2023) <doi:10.1201/9780429503658>.
Getting started
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Package details |
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| Author | Mohsen Soltanifar [aut] (<https://orcid.org/0000-0002-5989-0082>), Chel Hee Lee [cre, aut] (<https://orcid.org/0000-0001-8209-8176>) |
| Maintainer | Chel Hee Lee <chelhee.lee@ucalgary.ca> |
| License | GPL-3 |
| Version | 0.0.5 |
| Package repository | View on CRAN |
| Installation |
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