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A systematic biology tool was developed to identify dysregulated miRNAs via a miRNA-miRNA interaction network. 'IDMIR' first constructed a weighted miRNA interaction network through integrating miRNA-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific-disease context, and then, it used a network propagation algorithm on the network to identify significantly dysregulated miRNAs.
Package details |
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Author | Junwei Han [aut, cre, cph], Xilong Zhao [aut], Jiashuo Wu [aut] |
Maintainer | Junwei Han <hanjunwei1981@163.com> |
License | GPL (>= 2) |
Version | 0.1.0 |
Package repository | View on CRAN |
Installation |
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