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We developed the Integrated and Robust Deconvolution algorithm to infer cell-type proportions from target bulk RNA-seq data. This package is able to effectively integrate deconvolution results from multiple scRNA-seq datasets and calibrates estimates from reference-based deconvolution by taking into account extra biological information as priors. Moreover, the proposed algorithm is robust to inaccurate external information imposed in the deconvolution system.
Package details |
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Author | Chixiang Chen [cre, aut], Yuk Yee Leung [aut], Matei Lonita [aut], Li-San Wang [aut], Mingyao Li [aut] |
Maintainer | Chixiang Chen <chencxxy@hotmail.com> |
License | Artistic-2.0 |
Version | 0.1.1 |
URL | https://github.com/chencxxy28/InteRD |
Package repository | View on CRAN |
Installation |
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