Man pages for LTFGRS
Implementation of Several Phenotype-Based Family Genetic Risk Scores

attach_attributesAttach attributes to a family graphs
censor_family_onsetsCensor onset times in a family based on a proband's end of...
construct_covmatConstructing a covariance matrix for a variable number of...
construct_covmat_multiConstructing a covariance matrix for multiple phenotypes
construct_covmat_singleConstructing a covariance matrix for a single phenotype
convert_age_to_cirConvert age to cumulative incidence rate
convert_age_to_threshConvert age to threshold
convert_cir_to_ageConvert cumulative incidence rate to age
convert_formatAttempts to convert the list entry input format to a long...
convert_liability_to_aooConvert liability to age of onset
convert_observed_to_liability_scaleConvert the heritability on the observed scale to that on the...
correct_positive_definitePositive definite matrices
estimate_gen_liability_ltfhEstimate genetic liability similar to LT-FH
estimate_liabilityEstimating the genetic or full liability for a variable...
estimate_liability_multiEstimating the genetic or full liability for multiple...
estimate_liability_singleEstimating the genetic or full liability
extract_estimation_info_graphTitle Internal Function used to extact input needed from...
extract_estimation_info_tblTitle Internal Function used to extact input needed for...
familywise_attach_attributesWrapper to attach attributes to family graphs
familywise_censoringCensor Family Onsets for Multiple Families
fixSexCodingFixing sex coding in trio info
get_all_combsconstruct all combinations of input vector
get_covmatConstruct kinship matrix from graph
get_family_graphsAutomatically identify family members of degree n
get_onset_timeCalculate age of diagnosis, age at end of follow up, and...
get_relatednessRelatedness between a pair of family members
Gibbs_estimatorWrapper around the Gibbs Sampler that returns formatted...
graph_based_covariance_constructionConstructing covariance matrix from local family graph
graph_based_covariance_construction_multiConstructing covariance matrix from local family graph for...
graph_to_trioConvert from igraph to trio information
kendlerTitle Kendler's FGRS
kendler_family_calculationsTitle Helper function for Kendler's FGRS
LTFGRS-packageLTFGRS: Implementation of Several Phenotype-Based Family...
PA_algorithmTitle Pearson-Aitken algorithm to calculate mean values in...
prepare_graphConstruct graph from register information
prepare_thresholdsCalculate (personalised) thresholds based on CIPs.
rtmvnorm.gibbsGibbs Sampler for the truncated multivariate normal...
simulate_under_LTMSimulate under the liability threshold model.
simulate_under_LTM_multiSimulate under the liability threshold model (multiple...
simulate_under_LTM_singleSimulate under the liability threshold model (single...
tnorm_meanTitle: Calculate the mean of the truncated normal...
tnorm_mixture_conditionalTitle: Calculates mean and variance of mixture of two...
tnorm_varTitle: Calculate the variance of the truncated normal...
truncated_normal_cdfCDF for truncated normal distribution.
LTFGRS documentation built on Aug. 8, 2025, 7:17 p.m.