MALDIcellassay: Automated MALDI Cell Assays Using Dose-Response Curve Fitting

Conduct automated cell-based assays using Matrix-Assisted Laser Desorption/Ionization (MALDI) methods for high-throughput screening of signals responsive to treatments. The package efficiently identifies high variance signals and fits dose-response curves to them. Quality metrics such as Z', V', log2FC, and CRS are provided for evaluating the potential of signals as biomarkers. The methodologies were introduced by Weigt et al. (2018) <doi:10.1038/s41598-018-29677-z> and refined by Unger et al. (2021) <doi:10.1038/s41596-021-00624-z>.

Package details

AuthorThomas Enzlein [aut, cre, cph] (<https://orcid.org/0000-0003-1789-4090>)
MaintainerThomas Enzlein <t.enzlein@hs-mannheim.de>
LicenseMIT + file LICENSE
Version0.4.47
URL https://github.com/CeMOS-Mannheim/MALDIcellassay
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("MALDIcellassay")

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MALDIcellassay documentation built on Sept. 11, 2024, 8:29 p.m.