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PCAmatchR: Match Cases to Controls Based on Genotype Principal Components
Matches cases to controls based on genotype principal components (PC). In order to produce better results, matches are based on the weighted distance of PCs where the weights are equal to the % variance explained by that PC. A weighted Mahalanobis distance metric (Kidd et al. (1987) <DOI:10.1016/0031-3203(87)90066-5>) is used to determine matches.
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Package details |
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| Author | Derek W. Brown [aut, cre] (<https://orcid.org/0000-0001-8393-1713>), Mitchel J. Machiela [aut] (<https://orcid.org/0000-0001-6538-9705>), Timothy A. Myers [ctb] (<https://orcid.org/0000-0001-8127-3446>), NCI [cph, fnd] |
| Maintainer | Derek W. Brown <derek9@gwmail.gwu.edu> |
| License | MIT + file LICENSE |
| Version | 0.3.3 |
| URL | https://github.com/machiela-lab/PCAmatchR |
| Package repository | View on CRAN |
| Installation |
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