SCORPION: Single Cell Oriented Reconstruction of PANDA Individual Optimized Networks

Constructs cell-type–specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into supercells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor–target regulatory relationships. It also provides statistical methods for differential edge analysis.

Getting started

Package details

AuthorDaniel Osorio [aut, cre] (ORCID: <https://orcid.org/0000-0003-4424-8422>), Marieke L. Kuijjer [aut] (ORCID: <https://orcid.org/0000-0001-6280-3130>)
MaintainerDaniel Osorio <daniecos@uio.no>
LicenseGPL-3
Version1.3.1
URL https://github.com/kuijjerlab/SCORPION
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("SCORPION")

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SCORPION documentation built on Feb. 12, 2026, 5:07 p.m.