Analysis of Surface Plasmon Resonance (SPR) and Biolayer Interferometry data, with automations for high-throughput SPR. This version of the package fits the 1: 1 binding model, with and without bulkshift. It offers optional local or global Rmax fitting. The user must provide a sample sheet and a Carterra output file in Carterra's current format. There is a utility function to convert from Carterra's old output format. The user may run a custom pipeline or use the provided 'Runscript', which will produce a pdf file containing fitted Rmax, ka, kd and standard errors, a plot of the sensorgram and fits, and a plot of residuals. The script will also produce a .csv file with all of the relevant parameters for each spot on the SPR chip.
Package details |
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Author | Janice McCarthy Developer [aut, cre, cph], Kan Li Dev [aut], S. Moses Dennison [aut], Georgia D. Tomaras [aut] |
Maintainer | Janice McCarthy Developer <janice.mccarthy@duke.edu> |
License | GPL (>= 3) |
Version | 0.1.0 |
Package repository | View on CRAN |
Installation |
Install the latest version of this package by entering the following in R:
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