lotri: A Simple Way to Specify Symmetric, Block Diagonal Matrices

Provides a simple mechanism to specify a symmetric block diagonal matrices (often used for covariance matrices). This is based on the domain specific language implemented in 'nlmixr2' but expanded to create matrices in R generally instead of specifying parts of matrices to estimate. It has expanded to include some matrix manipulation functions that are generally useful for 'rxode2' and 'nlmixr2'.

Package details

AuthorMatthew L. Fidler [aut, cre] (ORCID: <https://orcid.org/0000-0001-8538-6691>), Bill Denney [ctb] (ORCID: <https://orcid.org/0000-0002-5759-428X>)
MaintainerMatthew L. Fidler <matthew.fidler@gmail.com>
LicenseGPL (>= 2)
Version1.0.1
URL https://nlmixr2.github.io/lotri/ https://github.com/nlmixr2/lotri
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("lotri")

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lotri documentation built on Aug. 8, 2025, 6:12 p.m.