metadeconfoundR: Covariate-Sensitive Analysis of Cross-Sectional High-Dimensional Data

Using non-parametric tests, naive associations between omics features and metadata in cross-sectional data-sets are detected. In a second step, confounding effects between metadata associated to the same omics feature are detected and labeled using nested post-hoc model comparison tests, as first described in Forslund, Chakaroun, Zimmermann-Kogadeeva, et al. (2021) <doi:10.1038/s41586-021-04177-9>. The generated output can be graphically summarized using the built-in plotting function.

Getting started

Package details

AuthorTill Birkner [aut, cre] (<https://orcid.org/0000-0003-2656-2821>), Sofia Kirke Forslund-Startceva [ctb] (<https://orcid.org/0000-0003-4285-6993>)
MaintainerTill Birkner <metadeconf@till-birkner.de>
LicenseGPL-2
Version1.0.2
URL https://github.com/TillBirkner/metadeconfoundR
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("metadeconfoundR")

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metadeconfoundR documentation built on June 25, 2024, 5:07 p.m.