mtdesign: Mander and Thompson Designs

Implements Mander & Thompson's (2010) <doi:10.1016/j.cct.2010.07.008> methods for two-stage designs optimal under the alternative hypothesis for phase II [cancer] trials. Also provides an implementation of Simon's (1989) <doi:10.1016/0197-2456(89)90015-9> original methodology and allows exploration of the operating characteristics of sub-optimal designs.

Getting started

Package details

AuthorJohn Kirkpatrick [aut, cre] (ORCID: <https://orcid.org/0000-0001-7790-3708>)
MaintainerJohn Kirkpatrick <mtdesign@puzzledface.net>
LicenseGPL (>= 3)
Version0.1.3
URL https://github.com/openpharma/mtdesign
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("mtdesign")

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mtdesign documentation built on Aug. 23, 2025, 9:08 a.m.