nlmixr2: Nonlinear Mixed Effects Models in Population PK/PD

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Getting started

Package details

AuthorMatthew Fidler [aut, cre] (<https://orcid.org/0000-0001-8538-6691>), Anne Keunecke [ctb], Rik Schoemaker [ctb] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [ctb] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [ctb], Mirjam Trame [ctb], John Harrold [ctb], Bill Denney [ctb] (<https://orcid.org/0000-0002-5759-428X>), Theodoros Papathanasiou [ctb], Richard Hooijmaijers [ctb]
MaintainerMatthew Fidler <matthew.fidler@gmail.com>
LicenseGPL (>= 3)
Version3.0.2
URL https://nlmixr2.org/ https://github.com/nlmixr2/nlmixr2/
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("nlmixr2")

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nlmixr2 documentation built on April 4, 2025, 2:36 a.m.