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An R implementation of quality control–based robust LOESS(local polynomial regression fitting) signal correction for metabolomics data analysis, described in Dunn, W., Broadhurst, D., Begley, P. et al. (2011) <doi:10.1038/nprot.2011.335>. The optimisation of LOESS's span parameter using generalized cross-validation (GCV) is provided as an option. In addition to signal correction, 'qcrlscR' includes some utility functions like batch shifting and data filtering.
Package details |
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Author | Wanchang Lin [aut, cre], Warwick Dunn [aut] |
Maintainer | Wanchang Lin <wanchanglin@hotmail.com> |
License | GPL (>= 2) |
Version | 0.1.3 |
URL | https://github.com/wanchanglin/qcrlscR |
Package repository | View on CRAN |
Installation |
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