When multiple Cox proportional hazard models are performed on clinical data (month or year and status) and a set of differential expressions of genes, the results (Hazard risks, z-scores and p-values) can be used to create gene-expression signatures. Weights are calculated using the survival p-values of genes and are utilized to calculate expression values of the signature across the selected genes in all patients in a cohort. A Single or multiple univariate or multivariate Cox proportional hazard survival analyses of the patients in one cohort can be performed by using the gene-expression signature and visualized using our survival plots.
Package details |
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Author | Yuan-De Tan [aut, cre] (<https://orcid.org/0000-0002-0364-2223>), Yuguang Ban [ctb] |
Maintainer | Yuan-De Tan <tanyuande@gmail.com> |
License | GPL (>= 3) |
Version | 1.0.0 |
Package repository | View on CRAN |
Installation |
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