tLagInterim: Interim Monitoring of Clinical Trials with Time-Lagged Outcome

Implements inverse and augmented inverse probability weighted estimators for common treatment effect parameters at an interim analysis with time-lagged outcome that may not be available for all enrolled subjects. Produces estimators, standard errors, and information that can be used to compute stopping boundaries using software that assumes that the estimators/test statistics have independent increments. Tsiatis, A. A. and Davidian, M., (2022) <doi:10.1002/sim.9580> .

Getting started

Package details

AuthorShannon T. Holloway [aut, cre], Marie Davidian [aut], Anastasios Tsiatis [aut]
MaintainerShannon T. Holloway <shannon.t.holloway@gmail.com>
LicenseGPL-2
Version1.1
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("tLagInterim")

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tLagInterim documentation built on June 10, 2025, 9:10 a.m.