Files in brockk/dosefinding
A Modular Approach to Dose-Finding Clinical Trials

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DESCRIPTION

NAMESPACE

NEWS.md R/boin12_logic.R R/boin12_rds.R R/boin12_selector.R R/boin_comb_selector.R R/boin_selector.R R/calculate_probabilities.R R/check_dose_selector_consistency.R R/check_simulations_consistency.R R/combo_selector.R R/combo_selector_factory.R R/convergence_plot.R R/correlated_patient_sample.R R/crystallised_dose_paths.R R/demand_n_at_dose.R R/derived_dose_selector.R R/derived_dose_selector_factory.R R/dfcrm_selector.R R/dont_skip_doses.R R/dose_escalation_table.R R/dose_finding_path_node.R R/dose_paths.R R/dose_selector_summary_methods.R R/eff_tox_selector.R R/eff_tox_selector_factory.R R/enforce_three_plus_three.R R/escalation-package.R R/expand_last_dose_to_cohort.R R/expit.R R/follow_path.R R/get_dose_paths.R R/get_empiric_crm_skeleton_weights.R R/get_potential_outcomes.R R/graph_paths.R R/helpers.R R/interface.R R/linear_tolerance_weight.R R/mtpi2_selector.R R/mtpi_selector.R R/num_cohort_outcomes.R R/num_dose_path_nodes.R R/outcomes_to_arrays.R R/parse_phase1_2_outcomes.R R/parse_phase1_outcomes.R R/patient_sample.R R/phase1_2_comb_sim.R R/phase1_2_dose_paths.R R/phase1_2_outcomes_to_cohorts.R R/phase1_2_sim.R R/phase1_dose_paths.R R/phase1_outcomes_to_cohorts.R R/phase1_sim.R R/phase1_tite_sim.R R/random_dose_selector.R R/select_boin12_obd.R R/select_boin_comb_mtd.R R/select_boin_mtd.R R/select_dose_by_cibp.R R/select_mtpi2_mtd.R R/select_mtpi_mtd.R R/select_tpi_mtd.R R/selector.R R/selector_factory.R R/simulate_compare.R R/simulate_trials.R R/simulations.R R/simulations_collection.R R/spread_paths.R R/stack_sims_vert.R R/stick_on_num_tox.R R/stop_at_n_selector.R R/stop_when_n_at_dose_selector.R R/stop_when_too_toxic.R R/stop_when_tox_ci_covered.R R/three_plus_three.R R/three_plus_three_selector.R R/tox_selector_factory.R R/tpi_selector.R R/trialr_crm_selector.R R/trialr_efftox_selector.R R/trialr_nbg_selector.R R/try_rescue_dose.R R/unadmit_untested.R R/wages_tait_selector.R README.Rmd README.md

Scratch/.gitignore

Scratch/AZ mTPI2 replication.R Scratch/Comparing trialr to bcrm.R Scratch/Control.R Scratch/EOSF BOIN-COMB.R Scratch/Iasonos.R Scratch/Investigation for Zac.R Scratch/Scratch.R Scratch/SweetingEtAl.R Scratch/TITE.R

Scratch/TODO.txt

Scratch/TPI with and without the final MTD selector.R Scratch/TPI-simulations.R Scratch/conor_decision_table.R Scratch/deprecated_correlated_patient_sample.R Scratch/dev_phase1_tite_sim.R Scratch/develop_dose_combos.R Scratch/follow_path in boin-comb.R Scratch/mTPI with and without the final MTD selector.R Scratch/mTPI-simulations.R Scratch/mTPI2-simulations.R Scratch/optionally_escalation_boin_comb.R Scratch/phase1_2_comb_sim_dev.R Scratch/sim_compare mTPI vs TPI.R Scratch/tite_crm_bug.R Scratch/tweak_dtps.R Scratch/tweak_iso_regression.R

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dose.Rproj

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man/fit.Rd man/follow_path.Rd man/get_boin.Rd man/get_boin12.Rd man/get_boin_comb.Rd man/get_dfcrm.Rd man/get_dfcrm_tite.Rd man/get_dose_combo_indices.Rd man/get_dose_paths.Rd man/get_empiric_crm_skeleton_weights.Rd man/get_mtpi.Rd man/get_mtpi2.Rd man/get_potential_outcomes.Rd man/get_random_selector.Rd man/get_three_plus_three.Rd man/get_tpi.Rd man/get_trialr_crm.Rd man/get_trialr_crm_tite.Rd man/get_trialr_efftox.Rd man/get_trialr_nbg.Rd man/get_trialr_nbg_tite.Rd man/get_wages_and_tait.Rd man/graph_paths.Rd man/is_randomising.Rd man/linear_follow_up_weight.Rd man/mean_prob_eff.Rd man/mean_prob_tox.Rd man/median_prob_eff.Rd man/median_prob_tox.Rd man/model_frame.Rd man/n_at_dose.Rd man/n_at_recommended_dose.Rd man/num_cohort_outcomes.Rd man/num_dose_path_nodes.Rd man/num_doses.Rd man/num_eff.Rd man/num_patients.Rd man/num_tox.Rd man/parse_phase1_2_outcomes.Rd man/parse_phase1_outcomes.Rd man/phase1_2_outcomes_to_cohorts.Rd man/phase1_outcomes_to_cohorts.Rd man/prob_administer.Rd man/prob_eff_quantile.Rd man/prob_recommend.Rd man/prob_tox_exceeds.Rd man/prob_tox_quantile.Rd man/prob_tox_samples.Rd man/recommended_dose.Rd man/select_boin12_obd.Rd man/select_boin_comb_mtd.Rd man/select_boin_mtd.Rd man/select_dose_by_cibp.Rd man/select_mtpi2_mtd.Rd man/select_mtpi_mtd.Rd man/select_tpi_mtd.Rd man/selector.Rd man/selector_factory.Rd man/simulate_compare.Rd man/simulate_trials.Rd man/simulation_function.Rd man/simulations.Rd man/simulations_collection.Rd man/spread_paths.Rd man/stack_sims_vert.Rd man/stick_on_num_tox.Rd man/stop_at_n.Rd man/stop_when_n_at_dose.Rd man/stop_when_too_toxic.Rd man/stop_when_tox_ci_covered.Rd man/supports_sampling.Rd man/three_plus_three.Rd man/tox.Rd man/tox_at_dose.Rd man/tox_limit.Rd man/tox_target.Rd man/trial_duration.Rd man/try_rescue_dose.Rd man/unadmit_untested.Rd man/utility.Rd man/weight.Rd

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brockk/dosefinding documentation built on April 5, 2025, 5:53 p.m.

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brockk/dosefinding
A Modular Approach to Dose-Finding Clinical Trials

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brockk/dosefinding A Modular Approach to Dose-Finding Clinical Trials

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A Modular Approach to Dose-Finding Clinical Trials

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A Modular Approach to Dose-Finding Clinical Trials