hyochoi/SCISSOR: Shape changes in selecting sample outliers in RNA-seq

SCISSOR (shape changes in selecting sample outliers in RNA-seq) aims for unsupervised screening of a range of structural alterations in RNA-seq data. SCISSOR considers a novel shape property of aligned short read data through a base-level pileup file. This intact and uncompressed view of RNA-seq profile enables the unbiased discovery of structural alterations by looking for anomalous shapes in expression. This approach holds promise for identifying otherwise obscured genetic aberrations. As a result, SCISSOR identifies known as well as novel aberrations including abnormal splicing, intra-/intergenic deletions, small indels, alternative transcription start/termination.

Getting started

Package details

MaintainerHyo Young Choi <lucienne1216@gmail.com>
LicenseWhat license is it under?
Version1.1.11
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("hyochoi/SCISSOR")
hyochoi/SCISSOR documentation built on July 6, 2022, 6:59 a.m.