paulklemm/trapdiff: Differential Gene Expression for bacTRAP/riboTRAP data based on DESeq2

The goal of this package is to have an automated interface for conducting RNA-seq analysis of riboTRAP and bacTRAP data. In this data, we have two measurements per sample: Input (the background) and IP (pulldown of a specific cell type). We call this *source*. Then we have a experimental *condition*, for example normal chow diet (NCD) and high fat diet (HFD). We are now interested in genes that are (1) enriched in our pulldown (IP) and (2) differentially expressed between our experimental condition (e.g. HFD vs NCD) in the IP.

Getting started

Package details

Maintainer
LicenseMIT + file LICENSE
Version0.3.4
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("paulklemm/trapdiff")
paulklemm/trapdiff documentation built on Nov. 12, 2022, 12:12 a.m.