phillipnicol/SITH: A Spatial Model of Intra-Tumor Heterogeneity

Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.

Getting started

Package details

AuthorPhillip B. Nicol
MaintainerPhillip B. Nicol <philnicol740@gmail.com>
LicenseGPL (>= 2)
Version1.1.0
URL https://github.com/phillipnicol/SITH
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("phillipnicol/SITH")
phillipnicol/SITH documentation built on April 4, 2024, 8:10 p.m.