uc-bd2k/iPAS: integrative Pathway Activity Signatures (iPAS)

This package provides functions for calculating pathway scores based on integrative Pathway Activity Signatures (iPAS). These signatures were created using the LINCS L1000 differential expression dataset. We integrate data across twelve cell lines and use machine learning methods to find genes whose expression consistently reacts to pathway perturbation.

Getting started

Package details

AuthorNicholas Clark
MaintainerNicholas Clark <nicholas.clark00@gmail.com>, Mario Medvedovic <medvedm@ucmail.uc.edu>
LicenseGPL-3
Version0.1.0
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("uc-bd2k/iPAS")
uc-bd2k/iPAS documentation built on May 27, 2022, 10:13 p.m.