umich-biostatistics/AEenrich: Adverse Event Enrichment Tests

We extend existing gene enrichment tests to perform adverse event enrichment analysis. Unlike the continuous gene expression data, adverse event data are counts. Therefore, adverse event data has many zeros and ties. We propose two enrichment tests. One is a modified Fisher's exact test based on pre-selected significant adverse events, while the other is based on a modified Kolmogorov-Smirnov statistic. We add Covariate adjustment to improve the analysis."Adverse event enrichment tests using VAERS" Shuoran Li, Lili Zhao (2020) <arXiv:2007.02266>.

Getting started

Package details

Maintainer
LicenseGPL-2
Version1.1.0
URL https://github.com/umich-biostatistics/AEenrich
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("umich-biostatistics/AEenrich")
umich-biostatistics/AEenrich documentation built on Sept. 22, 2022, 11:13 a.m.